Literature DB >> 21595722

Computational fluid dynamics design and analysis of a passively suspended Tesla pump left ventricular assist device.

Richard B Medvitz1, David A Boger, Valentin Izraelev, Gerson Rosenberg, Eric G Paterson.   

Abstract

This article summarizes the use of computational fluid dynamics (CFD) to design a novel suspended Tesla left ventricular assist device. Several design variants were analyzed to study the parameters affecting device performance. CFD was performed at pump speeds of 6500, 6750, and 7000 rpm and at flow rates varying from 3 to 7 liters per minute (LPM). The CFD showed that shortening the plates nearest the pump inlet reduced the separations formed beneath the upper plate leading edges and provided a more uniform flow distribution through the rotor gaps, both of which positively affected the device hydrodynamic performance. The final pump design was found to produce a head rise of 77 mm Hg with a hydraulic efficiency of 16% at the design conditions of 6 LPM through flow and a 6750 rpm rotation rate. To assess the device hemodynamics the strain rate fields were evaluated. The wall shear stresses demonstrated that the pump wall shear stresses were likely adequate to inhibit thrombus deposition. Finally, an integrated field hemolysis model was applied to the CFD results to assess the effects of design variation and operating conditions on the device hemolytic performance.
© 2010, Copyright the Authors. Artificial Organs © 2010, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

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Year:  2010        PMID: 21595722      PMCID: PMC3426443          DOI: 10.1111/j.1525-1594.2010.01087.x

Source DB:  PubMed          Journal:  Artif Organs        ISSN: 0160-564X            Impact factor:   3.094


  9 in total

1.  A tensor-based measure for estimating blood damage.

Authors:  Dhruv Arora; Marek Behr; Matteo Pasquali
Journal:  Artif Organs       Date:  2004-11       Impact factor: 3.094

2.  Fast three-dimensional numerical hemolysis approximation.

Authors:  André Garon; Marie-Isabelle Farinas
Journal:  Artif Organs       Date:  2004-11       Impact factor: 3.094

3.  Asymptotically consistent numerical approximation of hemolysis.

Authors:  Marie-Isabelle Farinas; André Garon; David Lacasse; Donatien N'dri
Journal:  J Biomech Eng       Date:  2006-10       Impact factor: 2.097

Review 4.  Research approaches for studying flow-induced thromboembolic complications in blood recirculating devices.

Authors:  Danny Bluestein
Journal:  Expert Rev Med Devices       Date:  2004-09       Impact factor: 3.166

5.  Estimation of shear stress-related blood damage in heart valve prostheses--in vitro comparison of 25 aortic valves.

Authors:  M Giersiepen; L J Wurzinger; R Opitz; H Reul
Journal:  Int J Artif Organs       Date:  1990-05       Impact factor: 1.595

6.  LDA measurements of mean velocity and Reynolds stress fields within an artificial heart ventricle.

Authors:  J T Baldwin; S Deutsch; D B Geselowitz; J M Tarbell
Journal:  J Biomech Eng       Date:  1994-05       Impact factor: 2.097

7.  A passively suspended Tesla pump left ventricular assist device.

Authors:  Valentin Izraelev; William J Weiss; Bryan Fritz; Raymond K Newswanger; Eric G Paterson; Alan Snyder; Richard B Medvitz; Joshua Cysyk; Walter E Pae; Dennis Hicks; Branka Lukic; Gerson Rosenberg
Journal:  ASAIO J       Date:  2009 Nov-Dec       Impact factor: 2.872

8.  Visualization and analysis of mural thrombogenesis on collagen, polyurethane and nylon.

Authors:  J A Hubbell; L V McIntire
Journal:  Biomaterials       Date:  1986-09       Impact factor: 12.479

9.  The effect of fluid shear and co-adsorbed proteins on the stability of immobilized fibrinogen and subsequent platelet interactions.

Authors:  V Balasubramanian; S M Slack
Journal:  J Biomater Sci Polym Ed       Date:  2002       Impact factor: 3.517

  9 in total
  1 in total

1.  Tesla-Based Blood Pump and Its Applications.

Authors:  Choon-Sik Jhun; Ray Newswanger; Joshua Cysyk; Branka Lukic; William Weiss; Gerson Rosenberg
Journal:  J Med Device       Date:  2013-12-05       Impact factor: 0.582

  1 in total

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