| Literature DB >> 2159392 |
A Cencetti1, M De Martino, E Graziani, S Maddali Bongi, C Palermo, E Pavari, M Zoppi.
Abstract
In twelve rheumatoid arthritis (RA) patients, receiving only nonsteroid anti-inflammatory therapy, superoxide anion (02-) generation by polymorphonuclear leucocytes (PMNs) was assessed by Cytochrome C reduction. The 02- production by non-activated PMNs in RA patients was significantly higher than in healthy controls. The 02- production by PMNs activated by zymosan and phorbol myristate acetate was significantly lower than in controls. PMNs from controls preincubated with rheumatoid sera generated higher 02- levels than the same PMNs incubated in normal sera.Entities:
Mesh:
Substances:
Year: 1990 PMID: 2159392 DOI: 10.1007/BF02030242
Source DB: PubMed Journal: Clin Rheumatol ISSN: 0770-3198 Impact factor: 2.980