Literature DB >> 2159302

Cellular pharmacology of 2',3'-didehydro-2',3'-dideoxythymidine (D4T) in human peripheral blood mononuclear cells.

Z Zhu1, H T Ho, M J Hitchcock, J P Sommadossi.   

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Year:  1990        PMID： 2159302     DOI： 10.1016/0006-2952(90)90418-k

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  11 in total

1.  Anti-human immunodeficiency virus type 1 activity, intracellular metabolism, and pharmacokinetic evaluation of 2'-deoxy-3'-oxa-4'-thiocytidine.

Authors:  J M de Muys; H Gourdeau; N Nguyen-Ba; D L Taylor; P S Ahmed; T Mansour; C Locas; N Richard; M A Wainberg; R F Rando
Journal:  Antimicrob Agents Chemother       Date:  1999-08       Impact factor: 5.191

Review 2.  Stavudine: an update of its use in the treatment of HIV infection.

Authors:  M Hurst; S Noble
Journal:  Drugs       Date:  1999-11       Impact factor: 9.546

3.  Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro.

Authors:  P G Hoggard; S Kewn; M G Barry; S H Khoo; D J Back
Journal:  Antimicrob Agents Chemother       Date:  1997-06       Impact factor: 5.191

Review 4.  Pharmacokinetic optimisation of antiretroviral therapy in patients with HIV infection.

Authors:  B N Stretcher
Journal:  Clin Pharmacokinet       Date:  1995-07       Impact factor: 6.447

5.  In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine.

Authors:  E M Cretton; Z Zhou; L B Kidd; H M McClure; S Kaul; M J Hitchcock; J P Sommadossi
Journal:  Antimicrob Agents Chemother       Date:  1993-09       Impact factor: 5.191

6.  In silico study supports the efficacy of a reduced dose regimen for stavudine.

Authors:  Selwyn J Hurwitz; Raymond F Schinazi
Journal:  Antiviral Res       Date:  2011-08-22       Impact factor: 5.970

Review 7.  Stavudine: a review of its pharmacodynamic and pharmacokinetic properties and clinical potential in HIV infection.

Authors:  A P Lea; D Faulds
Journal:  Drugs       Date:  1996-05       Impact factor: 9.546

8.  Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases.

Authors:  J M Cherrington; M D Fuller; A S Mulato; S J Allen; S C Kunder; M A Ussery; Z Lesnikowski; R F Schinazi; J P Sommadossi; M S Chen
Journal:  Antimicrob Agents Chemother       Date:  1996-05       Impact factor: 5.191

Review 9.  Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.

Authors:  J Balzarini
Journal:  Pharm World Sci       Date:  1994-04-15

10.  Intracellular nucleotides of (-)-2',3'-deoxy-3'-thiacytidine in peripheral blood mononuclear cells of a patient infected with human immunodeficiency virus.

Authors:  C Solas; Y F Li; M Y Xie; J P Sommadossi; X J Zhou
Journal:  Antimicrob Agents Chemother       Date:  1998-11       Impact factor: 5.191
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