Literature DB >> 21592988

Influence of variations in CCL3L1 and CCR5 on tuberculosis in a northwestern Colombian population.

Manju Mamtani1, Srinivas Mummidi, Veron Ramsuran, Minh-Hieu Pham, Robert Maldonado, Kazi Begum, Maria Soledad Valera, Racquel Sanchez, John Castiblanco, Hemant Kulkarni, Thumbi Ndung'u, Weijing He, Juan Manuel Anaya, Sunil K Ahuja.   

Abstract

We investigated the association of polymorphisms in CCR5, the major human immunodeficiency virus (HIV)-1 coreceptor, and copy number of its potent ligand CCL3L1 with tuberculosis in 298 individuals from Colombia. The CCR5-HHD haplotype, a known genetic determinant of increased susceptibility to HIV-AIDS, and a high copy number of CCL3L1, a known genetic determinant of enhanced CCL3/CCL3L1 chemokine expression, each associated with presence of tuberculosis. Furthermore, CCR5-HHD was associated with higher CCR5 gene and surface expression. These results substantiate the strong link between the pro-inflammatory effects of CCR5 and its ligands with active tuberculosis and suggest that chemokine-chemokine receptor genetic determinants may influence tuberculosis in addition to HIV/AIDS.

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Year:  2011        PMID： 21592988      PMCID： PMC3096789          DOI： 10.1093/infdis/jir145

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  16 in total

1.  Concordance of CCR5 genotypes that influence cell-mediated immunity and HIV-1 disease progression rates.

Authors:  Gabriel Catano; Zoya A Chykarenko; Andrea Mangano; J-M Anaya; Weijing He; Alison Smith; Rosa Bologna; Luisa Sen; Robert A Clark; Andrew Lloyd; Ludmila Shostakovich-Koretskaya; Sunil K Ahuja
Journal:  J Infect Dis       Date:  2011-01-15       Impact factor: 5.226

2.  Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered transcription factor binding to polymorphic nucleotides in the pathogenesis of HIV-1 and simian immunodeficiency virus.

Authors:  S Mummidi; M Bamshad; S S Ahuja; E Gonzalez; P M Feuillet; K Begum; M C Galvis; V Kostecki; A J Valente; K K Murthy; L Haro; M J Dolan; J S Allan; S K Ahuja
Journal:  J Biol Chem       Date:  2000-06-23       Impact factor: 5.157

3.  CCR5 promoter polymorphisms in a Kenyan perinatal human immunodeficiency virus type 1 cohort: association with increased 2-year maternal mortality.

Authors:  G C John; T Bird; J Overbaugh; R Nduati; D Mbori-Ngacha; T Rostron; T Dong; L Kostrikis; B Richardson; S L Rowland-Jones
Journal:  J Infect Dis       Date:  2001-05-31       Impact factor: 5.226

4.  A polymorphism in the regulatory region of the CC-chemokine receptor 5 gene influences perinatal transmission of human immunodeficiency virus type 1 to African-American infants.

Authors:  L G Kostrikis; A U Neumann; B Thomson; B T Korber; P McHardy; R Karanicolas; L Deutsch; Y Huang; J F Lew; K McIntosh; H Pollack; W Borkowsky; H M Spiegel; P Palumbo; J Oleske; A Bardeguez; K Luzuriaga; J Sullivan; S M Wolinsky; R A Koup; D D Ho; J P Moore
Journal:  J Virol       Date:  1999-12       Impact factor: 5.103

Review 5.  Current findings, challenges and novel approaches in human genetic susceptibility to tuberculosis.

Authors:  Marlo Möller; Eileen G Hoal
Journal:  Tuberculosis (Edinb)       Date:  2010-03-04       Impact factor: 3.131

6.  CCR2 and CCR5 genotypes in HIV type 1-infected adolescents: limited contributions to variability in plasma HIV type 1 RNA concentration in the absence of antiretroviral therapy.

Authors:  Jianming Tang; Craig M Wilson; Margaret Schaen; Angela Myracle; Steven D Douglas; Richard A Kaslow
Journal:  AIDS Res Hum Retroviruses       Date:  2002-04-10       Impact factor: 2.205

7.  Severe tuberculosis induces unbalanced up-regulation of gene networks and overexpression of IL-22, MIP-1alpha, CCL27, IP-10, CCR4, CCR5, CXCR3, PD1, PDL2, IL-3, IFN-beta, TIM1, and TLR2 but low antigen-specific cellular responses.

Authors:  Liyou Qiu; Dan Huang; Cystal Y Chen; Richard Wang; Ling Shen; Yun Shen; Robert Hunt; James Estep; Barton F Haynes; William R Jacobs; Norman Letvin; George Du; Zheng W Chen
Journal:  J Infect Dis       Date:  2008-11-15       Impact factor: 5.226

8.  In mice, tuberculosis progression is associated with intensive inflammatory response and the accumulation of Gr-1 cells in the lungs.

Authors:  Irina V Lyadova; Evgeny N Tsiganov; Marina A Kapina; Galena S Shepelkova; Vasily V Sosunov; Tatiana V Radaeva; Konstantin B Majorov; Natalya S Shmitova; Henk-Jan van den Ham; Vitaly V Ganusov; Rob J De Boer; Rachael Racine; Gary M Winslow
Journal:  PLoS One       Date:  2010-05-04       Impact factor: 3.240

9.  CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation.

Authors:  Jose F Camargo; Marlon P Quinones; Srinivas Mummidi; Sowmya Srinivas; Alvaro A Gaitan; Kazi Begum; Fabio Jimenez; Scott VanCompernolle; Derya Unutmaz; Seema S Ahuja; Sunil K Ahuja
Journal:  J Immunol       Date:  2009-01-01       Impact factor: 5.422

10.  Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians.

Authors:  Rakhi Malhotra; Liangyuan Hu; Wei Song; Ilene Brill; Joseph Mulenga; Susan Allen; Eric Hunter; Sadeep Shrestha; Jianming Tang; Richard A Kaslow
Journal:  Retrovirology       Date:  2011-03-23       Impact factor: 4.602
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  10 in total

1.  CCR5 promoter haplotypes differentially influence CCR5 expression on natural killer and T cell subsets in ethnically divergent HIV-1 uninfected South African populations.

Authors:  Anabela C P Picton; Maria Paximadis; Caroline T Tiemessen
Journal:  Immunogenetics       Date:  2012-08-15       Impact factor: 2.846

2.  A functional single-nucleotide polymorphism in the promoter of the gene encoding interleukin 6 is associated with susceptibility to tuberculosis.

Authors:  Guoliang Zhang; Boping Zhou; Wenfei Wang; Mingxia Zhang; Yahua Zhao; Zheng Wang; Lin Yang; Jingnan Zhai; Carl G Feng; Junwen Wang; Xinchun Chen
Journal:  J Infect Dis       Date:  2012-03-28       Impact factor: 5.226

Review 3.  The immunological life cycle of tuberculosis.

Authors:  Joel D Ernst
Journal:  Nat Rev Immunol       Date:  2012-07-13       Impact factor: 53.106

4.  CCL3L1 copy number, CCR5 genotype and susceptibility to tuberculosis.

Authors:  Danielle Carpenter; Carmen Taype; Jon Goulding; Mike Levin; Brian Eley; Suzanne Anderson; Marie-Anne Shaw; John A L Armour
Journal:  BMC Med Genet       Date:  2014-01-09       Impact factor: 2.103

5.  The variations of IL-23R are associated with susceptibility and severe clinical forms of pulmonary tuberculosis in Chinese Uygurs.

Authors:  Daobin Jiang; Atikaimu Wubuli; Xin Hu; Syed Ikramullah; Abudoujilili Maimaiti; Wenbao Zhang; Qimanguli Wushouer
Journal:  BMC Infect Dis       Date:  2015-12-01       Impact factor: 3.090

6.  Association of chemotactic chemokine ligand 5 rs2107538 polymorphism with tuberculosis susceptibility: A meta-analysis.

Authors:  Yun-Feng Sheng; Qi Qi
Journal:  Innate Immun       Date:  2019-12-25       Impact factor: 2.680

7.  CCR5 Promoter Polymorphisms Associated With Pulmonary Tuberculosis in a Chinese Han Population.

Authors:  Shuyuan Liu; Nannan Liu; Hui Wang; Xinwen Zhang; Yufeng Yao; Shuqiong Zhang; Li Shi
Journal:  Front Immunol       Date:  2021-02-19       Impact factor: 7.561

8.  Reduced CCR5 Expression and Immune Quiescence in Black South African HIV-1 Controllers.

Authors:  Anabela C P Picton; Maria Paximadis; Gemma W Koor; Avani Bharuthram; Sharon Shalekoff; Ria Lassauniere; Prudence Ive; Caroline T Tiemessen
Journal:  Front Immunol       Date:  2021-12-20       Impact factor: 7.561

9.  CCL3L1 copy number, HIV load, and immune reconstitution in sub-Saharan Africans.

Authors:  Eleni Aklillu; Linda Odenthal-Hesse; Jennifer Bowdrey; Abiy Habtewold; Eliford Ngaimisi; Getnet Yimer; Wondwossen Amogne; Sabina Mugusi; Omary Minzi; Eyasu Makonnen; Mohammed Janabi; Ferdinand Mugusi; Getachew Aderaye; Robert Hardwick; Beiyuan Fu; Maria Viskaduraki; Fengtang Yang; Edward J Hollox
Journal:  BMC Infect Dis       Date:  2013-11-12       Impact factor: 3.090

10.  Copy number variation of CCL3L1 among three major ethnic groups in Malaysia.

Authors:  Jalilah Jamaluddin; Nur Khairina Mohd Khair; Shameni Devi Vinodamaney; Zulkefley Othman; Suhaili Abubakar
Journal:  BMC Genet       Date:  2020-01-03       Impact factor: 2.797
  10 in total

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