| Literature DB >> 21592669 |
L Chitimia1, C I Muñoz-García, D Sánchez-Velasco, V Lizana, L Del Río, L Murcia, R Fisa, C Riera, P Giménez-Font, P Jiménez-Montalbán, A Martínez-Ramírez, J M Meseguer-Meseguer, I García-Bacete, M A Sánchez-Isarria, G Sanchis-Monsonís, J D García-Martínez, V Vicente, M Segovia, E Berriatua.
Abstract
An epidemiological study was carried out to investigate asymptomatic Leishmania infantum infection by PCR and ELISA in wild rabbits, humans and domestic dogs in southeastern Spain. Seroprevalence was 0% (0/36) in rabbits, 2% (13/657) in humans and 7% (14/208) in dogs. The prevalence of PCR-positives was 0.6% (1/162) in rabbits tested in a wide range of tissue samples, 2% (8/392) in humans analysed in blood samples and 10% (20/193) and 67% (29/43) in dogs analysed in blood and lymphoid tissue samples, respectively. Results suggest that wild rabbits have a very low risk of becoming chronically infected with L. infantum, and provide further evidence that cryptic L. infantum infection is widespread in the domestic dog population and is also present in a comparatively smaller proportion of healthy humans. The epidemiological and clinical implications of these findings are discussed.Entities:
Mesh：
Year: 2011 PMID： 21592669 DOI： 10.1016/j.vetpar.2011.04.016
Source DB: PubMed Journal: Vet Parasitol ISSN： 0304-4017 Impact factor: 2.738