| Literature DB >> 21591695 |
Hidetsugu Tabata1, Naoya Wada, Yuko Takada, Tetsuta Oshitari, Hideyo Takahashi, Hideaki Natsugari.
Abstract
The atropisomeric properties of seven-membered-ring benzolactams (7a-c and 8a) [1,5-benzodiazepin-2-one (a), 1,5-benzothiazepin-4-one (b), and 1-benzazepin-2-one (c)] were examined. The atropisomers were isolated as the diastereomers with an (S)-phenethylamide moiety, which were characterized by X-ray crystallography, and the barriers to their interconversion were clarified.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21591695 DOI： 10.1021/jo2008725
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354