Literature DB >> 21590321

[Growth hormone therapy in adult patients: a review].

Peter Herbert Kann1.   

Abstract

Growth hormone deficiency (GHD) can frequently be expected in hypopituitarism of adult patients. If GHD is proven by dynamic testing of the somatotrophic axis, growth hormone substitution is useful for improving quality of life, body composition, bone and lipid metabolism, and myocardial function according to the criteria of evidence-based medicine and is admitted by most national health authorities. There are no other reasonable indications for growth hormone treatment in adulthood.

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Year:  2011        PMID： 21590321     DOI： 10.1007/s00508-011-1574-7

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN： 0043-5325            Impact factor:   1.704


  88 in total

1.  The influence of growth hormone deficiency, growth hormone replacement therapy, and other aspects of hypopituitarism on fracture rate and bone mineral density. .

Authors:  C Wüster; R Abs; B A Bengtsson; H Bennmarker; U Feldt-Rasmussen; E Hernberg-Ståhl; J P Monson; B Westberg; P Wilton
Journal:  J Bone Miner Res       Date:  2001-02       Impact factor: 6.741

2.  Effect of growth hormone on osteoblasts and demonstration of somatomedin-C/IGF I in bone organ culture.

Authors:  H Stracke; A Schulz; D Moeller; S Rossol; H Schatz
Journal:  Acta Endocrinol (Copenh)       Date:  1984-09

3.  The prevalence of the metabolic syndrome is increased in patients with GH deficiency, irrespective of long-term substitution with recombinant human GH.

Authors:  Agatha A van der Klaauw; Nienke R Biermasz; Edith J M Feskens; Marieke B Bos; Johannes W A Smit; Ferdinand Roelfsema; Eleonora P M Corssmit; Hanno Pijl; Johannes A Romijn; Alberto M Pereira
Journal:  Eur J Endocrinol       Date:  2007-04       Impact factor: 6.664

4.  Withdrawal of long-term physiological growth hormone (GH) administration: differential effects on bone density and body composition in men with adult-onset GH deficiency.

Authors:  B M Biller; G Sesmilo; H B Baum; D Hayden; D Schoenfeld; A Klibanski
Journal:  J Clin Endocrinol Metab       Date:  2000-03       Impact factor: 5.958

5.  New markers of bone and collagen turnover in children and adults with growth hormone deficiency.

Authors:  A Sartorio; A Conti; M Monzani
Journal:  Postgrad Med J       Date:  1993-11       Impact factor: 2.401

6.  Effects of human growth hormone in men over 60 years old.

Authors:  D Rudman; A G Feller; H S Nagraj; G A Gergans; P Y Lalitha; A F Goldberg; R A Schlenker; L Cohn; I W Rudman; D E Mattson
Journal:  N Engl J Med       Date:  1990-07-05       Impact factor: 91.245

7.  Consequences of childhood-onset growth hormone deficiency for adult bone mass.

Authors:  H de Boer; G J Blok; A van Lingen; G J Teule; P Lips; E A van der Veen
Journal:  J Bone Miner Res       Date:  1994-08       Impact factor: 6.741

Review 8.  Cardiovascular risk factors in hypopituitary GH-deficient adults.

Authors:  Johan Verhelst; Roger Abs
Journal:  Eur J Endocrinol       Date:  2009-08-14       Impact factor: 6.664

9.  Evaluation of the optimum dose of growth hormone (GH) for restoring bone mass in adult-onset GH deficiency: results from two 12-month randomized studies.

Authors:  B Abrahamsen; J Hangaard; H C Horn; T B Hansen; G Gregersen; M Hansen-Nord; N Vahl; P Junker; M Andersen; C Hagen
Journal:  Clin Endocrinol (Oxf)       Date:  2002-08       Impact factor: 3.478

10.  Effect of long-term treatment with GH on bone metabolism, bone mineral density and bone elasticity in GH-deficient adults.

Authors:  P Kann; B Piepkorn; B Schehler; J Andreas; J Lotz; W Prellwitz; J Beyer
Journal:  Clin Endocrinol (Oxf)       Date:  1998-05       Impact factor: 3.478
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  2 in total

Review 1.  [Pituitary coma].

Authors:  P H Kann
Journal:  Med Klin Intensivmed Notfmed       Date:  2012-08-23       Impact factor: 0.840

Review 2.  Improving Quality of Life in Patients with Pituitary Tumours.

Authors:  Iris Crespo; Alicia Santos; Eugenia Resmini; Elena Valassi; Maria Antonia Martínez-Momblán; Susan M Webb
Journal:  Eur Endocrinol       Date:  2013-03-15
  2 in total

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