Literature DB >> 21587004

Development of an integrated psychosocial treatment to address the medical burden associated with bipolar disorder.

Louisa G Sylvia1, Andrew A Nierenberg, Jonathan P Stange, Andrew D Peckham, Thilo Deckersbach.   

Abstract

We developed an integrated psychosocial treatment for bipolar disorder to decrease the disproportionate medical burden associated with this illness. Three treatment modules, Nutrition/weight loss, Exercise, and Wellness Treatment (NEW Tx) were administered in twelve 60-minute group sessions over 14 weeks. After the first group (N=4) had completed the treatment, it was revised, and then a second group (N=6) completed the revised treatment. Participants completed all of the study assessments and attended 82% of the sessions. Both groups added over 100 minutes of weekly exercise to their baseline duration. Participants in the second group showed improvements in their quality of life, depressive symptoms, and weight. It appears that NEW Tx may be a feasible intervention with promising pilot data for reducing the medical burden in bipolar disorder, but future research is needed to further evaluate the efficacy of NEW Tx.

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Year:  2011        PMID: 21587004      PMCID: PMC3659403          DOI: 10.1097/01.pra.0000398419.82362.32

Source DB:  PubMed          Journal:  J Psychiatr Pract        ISSN: 1527-4160            Impact factor:   1.325


  47 in total

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3.  Relative sensitivity of the Montgomery-Asberg Depression Rating Scale, the Hamilton Depression rating scale and the Clinical Global Impressions rating scale in antidepressant clinical trials.

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4.  Cognitive behavioral therapy for treatment of chronic primary insomnia: a randomized controlled trial.

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5.  Effects of exercise training on older patients with major depression.

Authors:  J A Blumenthal; M A Babyak; K A Moore; W E Craighead; S Herman; P Khatri; R Waugh; M A Napolitano; L M Forman; M Appelbaum; P M Doraiswamy; K R Krishnan
Journal:  Arch Intern Med       Date:  1999-10-25

6.  Determinants of overweight and obesity in patients with bipolar disorder.

Authors:  J L Elmslie; J I Mann; J T Silverstone; S M Williams; S E Romans
Journal:  J Clin Psychiatry       Date:  2001-06       Impact factor: 4.384

7.  A brief assessment of psychosocial functioning of subjects with bipolar I disorder: the LIFE-RIFT. Longitudinal Interval Follow-up Evaluation-Range Impaired Functioning Tool.

Authors:  A C Leon; D A Solomon; T I Mueller; J Endicott; M Posternak; L L Judd; P J Schettler; H S Akiskal; M B Keller
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8.  The effectiveness of exercise as an intervention in the management of depression: systematic review and meta-regression analysis of randomised controlled trials.

Authors:  D A Lawlor; S W Hopker
Journal:  BMJ       Date:  2001-03-31

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  12 in total

1.  Physical Activity as a Predictor of Clinical Trial Outcomes in Bipolar Depression: A Subanalysis of a Mitochondrial-Enhancing Nutraceutical Randomized Controlled Trial.

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2.  Transdiagnostic treatment of bipolar disorder and comorbid anxiety with the unified protocol: a clinical replication series.

Authors:  Kristen K Ellard; Thilo Deckersbach; Louisa G Sylvia; Andrew A Nierenberg; David H Barlow
Journal:  Behav Modif       Date:  2012-07-19

Review 3.  Lifestyle interventions targeting dietary habits and exercise in bipolar disorder: A systematic review.

Authors:  Isabelle E Bauer; Juan F Gálvez; Jane E Hamilton; Vicent Balanzá-Martínez; Giovana B Zunta-Soares; Jair C Soares; Thomas D Meyer
Journal:  J Psychiatr Res       Date:  2015-12-12       Impact factor: 4.791

4.  Cardiometabolic Health in Bipolar Disorder.

Authors:  David E Kemp; Jinbo Fan
Journal:  Psychiatr Ann       Date:  2012-05-01

5.  A brief review of exercise, bipolar disorder, and mechanistic pathways.

Authors:  Daniel Thomson; Alyna Turner; Sue Lauder; Margaret E Gigler; Lesley Berk; Ajeet B Singh; Julie A Pasco; Michael Berk; Louisa Sylvia
Journal:  Front Psychol       Date:  2015-03-04

Review 6.  Physical Activity Modulates Common Neuroplasticity Substrates in Major Depressive and Bipolar Disorder.

Authors:  Cristy Phillips
Journal:  Neural Plast       Date:  2017-04-26       Impact factor: 3.599

7.  Feasibility and Acceptability of a Lifestyle Intervention For Individuals With Bipolar Disorder.

Authors:  Louisa G Sylvia; Jessica A Janos; Samantha L Pegg; Steven C Dufour; Weilynn C Chang; Emily E Bernstein; Brett Davis; Kristen K Ellard; Thilo Deckersbach; Andrew A Nierenberg
Journal:  J Psychiatr Pract       Date:  2019-11       Impact factor: 1.841

8.  Nutrition, Exercise, and Wellness Treatment in bipolar disorder: proof of concept for a consolidated intervention.

Authors:  Louisa G Sylvia; Stephanie Salcedo; Emily E Bernstein; Ji Hyun Baek; Andrew A Nierenberg; Thilo Deckersbach
Journal:  Int J Bipolar Disord       Date:  2013-10-01

9.  The Impact of General Medical Conditions in Obsessive-Compulsive Disorder.

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10.  The Effect of DHA Supplementation on Cognition in Patients with Bipolar Disorder: An Exploratory Randomized Control Trial.

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Journal:  Nutrients       Date:  2020-03-06       Impact factor: 5.717

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