| Literature DB >> 21585789 |
V Rougeron1, E Waleckx, M Hide, T DE Meeûs, J Arevalo, A Llanos-Cuentas, A L Bañuls.
Abstract
Twelve microsatellite loci of Leishmania braziliensis were examined, nine of which were developed in this work. Fifty-six Leishmania braziliensis were genotyped with these microsatellite loci. The 12 loci studied were polymorphic with the number of alleles ranging from five to 19, with a mean of 9.7 ± 4.1 and the observed heterozygosity averaging 0.425 ± 0.202. The important heterozygote deficits we observed (F(IS) = 0.41, P value = 0.004) appear incompatible with the heterozygote excess expected in clonal diploids. This last result could revive the clonality/sexuality debate regarding Leishmania. This work validates the potential use of these microsatellites for population genetics analysis.Entities:
Year: 2008 PMID: 21585789 DOI: 10.1111/j.1471-8286.2007.01953.x
Source DB: PubMed Journal: Mol Ecol Resour ISSN: 1755-098X Impact factor: 7.090