Literature DB >> 21585300

Research in bioanalysis and separations at the University of Nebraska - Lincoln.

David S Hage1, Eric D Dodds, Liangcheng Du, Robert Powers.   

Abstract

The Chemistry Department at the University of Nebraska - Lincoln (UNL) is located in Hamilton Hall on the main campus of UNL in Lincoln, NE, USA. This department houses the primary graduate and research program in chemistry in the state of Nebraska. This program includes the traditional fields of analytical chemistry, biochemistry, inorganic chemistry, organic chemistry and physical chemistry. However, this program also contains a great deal of multidisciplinary research in fields that range from bioanalytical and biophysical chemistry to nanomaterials, energy research, catalysis and computational chemistry. Current research in bioanalytical and biophysical chemistry at UNL includes work with separation methods such as HPLC and CE, as well as with techniques such as MS and LC-MS, NMR spectroscopy, electrochemical biosensors, scanning probe microscopy and laser spectroscopy. This article will discuss several of these areas, with an emphasis being placed on research in bioanalytical separations, binding assays and related fields.

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Year:  2011        PMID: 21585300      PMCID: PMC3134374          DOI: 10.4155/bio.11.64

Source DB:  PubMed          Journal:  Bioanalysis        ISSN: 1757-6180            Impact factor:   2.681


  79 in total

1.  Immobilization of alpha(1)-acid glycoprotein for chromatographic studies of drug-protein binding.

Authors:  Hai Xuan; David S Hage
Journal:  Anal Biochem       Date:  2005-09-19       Impact factor: 3.365

2.  Negative impact of noise on the principal component analysis of NMR data.

Authors:  Steven Halouska; Robert Powers
Journal:  J Magn Reson       Date:  2005-09-27       Impact factor: 2.229

3.  Comparison of protein active site structures for functional annotation of proteins and drug design.

Authors:  Robert Powers; Jennifer C Copeland; Katherine Germer; Kelly A Mercier; Viswanathan Ramanathan; Peter Revesz
Journal:  Proteins       Date:  2006-10-01

Review 4.  Recent advances in chromatographic and electrophoretic methods for the study of drug-protein interactions.

Authors:  D S Hage; S A Tweed
Journal:  J Chromatogr B Biomed Sci Appl       Date:  1997-10-10

5.  Chromatographic analysis of carbamazepine binding to human serum albumin. II. Comparison of the Schiff base and N-hydroxysuccinimide immobilization methods.

Authors:  Hee Seung Kim; Rangan Mallik; David S Hage
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2006-05-09       Impact factor: 3.205

6.  Evaluation of a hydrazide-linked alpha1-acid glycoprotein chiral stationary phase: separation of R- and S-propranolol.

Authors:  Hai Xuan; David S Hage
Journal:  J Sep Sci       Date:  2006-07       Impact factor: 3.645

7.  Chromatographic analysis of carbamazepine binding to human serum albumin.

Authors:  Hee Seung Kim; David S Hage
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2005-02-25       Impact factor: 3.205

8.  Studies of protein binding to nonpolar solutes by using zonal elution and high-performance affinity chromatography: interactions of cis- and trans-clomiphene with human serum albumin in the presence of beta-cyclodextrin.

Authors:  D S Hage; A Sengupta
Journal:  Anal Chem       Date:  1998-11-01       Impact factor: 6.986

9.  A multi-step NMR screen for the identification and evaluation of chemical leads for drug discovery.

Authors:  Kelly A Mercier; Matthew D Shortridge; Robert Powers
Journal:  Comb Chem High Throughput Screen       Date:  2009-03       Impact factor: 1.339

10.  Evaluation of silica monoliths in affinity microcolumns for high-throughput analysis of drug-protein interactions.

Authors:  Michelle J Yoo; David S Hage
Journal:  J Sep Sci       Date:  2009-08       Impact factor: 3.645

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