Literature DB >> 21585185

Polypharmacy and decreased cognitive abilities in elderly patients.

Alma Alic1, Nurka Pranjic, Enisa Ramic.   

Abstract

GOAL: To estimate the prevalence of poly pharmacy and poly pharmacy effect on decline in cognitive abilities of randomly selected group of people over 65.
METHODOLOGY: A preliminary pilot study was based on the results of other researchers. 54 patients over 65 were randomly interviewed. Poly pharmacy was defined as using 23 drugs. "A short portable mental status questionnaire" was used in estimating decline of cognitive abilities.
RESULTS: According to the study results it was concluded that prevalence of poly pharmacy by the elderly is significant--48.1%. Most present drugs are the ones treating cardiovascular disease, anti diabetic, anti-inflammatory drugs, long acting benzodiazepines, antihistamines. Of the total respondents 33.3% of them live alone and do not have adequate supervision. We have found that poly pharmacy resulted in decline of cognitive abilities in 23 of 54 patients tested in rapid mental status check.
CONCLUSION: It is necessary to conduct future research on this issue.

Entities:  

Mesh:

Year:  2011        PMID: 21585185

Source DB:  PubMed          Journal:  Med Arh        ISSN: 0350-199X


  7 in total

1.  Issues potentially affecting quality of life arising from long-term medicines use: a qualitative study.

Authors:  Janet Krska; Charles W Morecroft; Helen Poole; Philip H Rowe
Journal:  Int J Clin Pharm       Date:  2013-08-29

2.  Psychotropic drug use and cognitive rehabilitation practice for elderly patients.

Authors:  Eiji Kose; Toshiyuki Hirai; Toshiichi Seki
Journal:  Int J Clin Pharm       Date:  2018-08-21

3.  Use patterns of over-the-counter (OTC) medications and perspectives on OTC medications among Korean adult patients with chronic diseases: gender and age differences.

Authors:  Hyun Jeong Kim; Young-Mo Yang; Eun Joo Choi
Journal:  Patient Prefer Adherence       Date:  2018-08-28       Impact factor: 2.711

4.  Pain characteristics and incidence of functional disability among community-dwelling older adults.

Authors:  Keitaro Makino; Sangyoon Lee; Seongryu Bae; Songee Jung; Yohei Shinkai; Ippei Chiba; Hiroyuki Shimada
Journal:  PLoS One       Date:  2019-04-15       Impact factor: 3.240

5.  Prevalence of polypharmacy and drug interaction among hospitalized patients: opportunities and responsabilities in pharmaceutical care.

Authors:  Edisa Trumic; Nurka Pranjic; Lejla Begic; Fahir Bečić
Journal:  Mater Sociomed       Date:  2012

Review 6.  What is polypharmacy? A systematic review of definitions.

Authors:  Nashwa Masnoon; Sepehr Shakib; Lisa Kalisch-Ellett; Gillian E Caughey
Journal:  BMC Geriatr       Date:  2017-10-10       Impact factor: 4.070

7.  Polypharmacy Is Associated with Lower Memory Function in African American Older Adults.

Authors:  Shervin Assari; Cheryl Wisseh; Mohammed Saqib; Mohsen Bazargan
Journal:  Brain Sci       Date:  2020-01-16
  7 in total

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