Literature DB >> 21580392

(1R*,2R*)-1-(7-Bromo-3-methoxy-naphthalen-2-yl)-4-(dimethyl-amino)-2-(naphthalen-1-yl)-1-phenyl-butan-2-ol.

Ping Liu, Wu Zhong, Pengfei Chen, Xiaohong Yang, Song Li.   

Abstract

In the crystal structure of the title compound, C(33)H(32)BrNO(2), the naphthalene ring system and the benzene ring are oriented at dihedral angles of 82.24 (4) and 79.53 (4)°, respectively, to the quinoline ring system. An intra-molecular O-H⋯N hydrogen bond occurs between the hydr-oxy H atom and the amine N atom.

Entities:  

Year:  2010        PMID: 21580392      PMCID: PMC2983564          DOI: 10.1107/S1600536810005209

Source DB:  PubMed          Journal:  Acta Crystallogr Sect E Struct Rep Online        ISSN: 1600-5368


  3 in total

1.  A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis.

Authors:  Koen Andries; Peter Verhasselt; Jerome Guillemont; Hinrich W H Göhlmann; Jean-Marc Neefs; Hans Winkler; Jef Van Gestel; Philip Timmerman; Min Zhu; Ennis Lee; Peter Williams; Didier de Chaffoy; Emma Huitric; Sven Hoffner; Emmanuelle Cambau; Chantal Truffot-Pernot; Nacer Lounis; Vincent Jarlier
Journal:  Science       Date:  2004-12-09       Impact factor: 47.728

2.  Medicine. New TB drug promises shorter, simpler treatment.

Authors:  Jon Cohen
Journal:  Science       Date:  2004-12-10       Impact factor: 47.728

3.  A short history of SHELX.

Authors:  George M Sheldrick
Journal:  Acta Crystallogr A       Date:  2007-12-21       Impact factor: 2.290

  3 in total

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