Ethyl 4-(dimethyl-amino)benzoate.

Mol-ecules of the title compound, C(11)H(15)NO(2), are essentially planar (r.m.s. deviation = 0.035 Å) and are linked into a chain along the a axis by weak C-H⋯O hydrogen bonds.

Related literature

Benzoic acid and its derivatives are good inhibitors of influenza viruses, see: Luo et al. (1995 ▶). For the use of benzoic acid derivatives such as 4-amino­benzoic acid as bifunctional organic ligands due to the variety of their coordination modes, see: Amiraslanov et al. (1979 ▶); Chen & Chen (2002 ▶); Hauptmann et al. (2000 ▶). For the use of the title compound as a part of a self-curing two-part system comprising degradable copolymers with applications in medicine and dentistry as root-canal sealants, root-canal filling materials, dental restorative materials, implant materials, bone cements and pulp-capping materials, see: Jia & Jin (2004 ▶).

Experimental

Crystal data

C11H15NO2

M = 193.24

Monoclinic,

a = 12.6949 (8) Å

b = 6.6596 (4) Å

c = 12.8529 (9) Å

β = 98.672 (11)°

V = 1074.20 (12) Å3

Z = 4

Mo Kα radiation

μ = 0.08 mm−1

T = 293 K

0.18 × 0.15 × 0.13 mm

Data collection

Nonius MACH-3 diffractometer

Absorption correction: ψ scan (North et al., 1968 ▶) T min = 0.985, T max = 0.989

4088 measured reflections

1873 independent reflections

1424 reflections with I > 2σ(I)

R int = 0.051

3 standard reflections every 60 min intensity decay: none

Refinement

R[F 2 > 2σ(F 2)] = 0.043

wR(F 2) = 0.134

S = 1.05

1873 reflections

131 parameters

H-atom parameters constrained

Δρmax = 0.16 e Å−3

Δρmin = −0.14 e Å−3

Data collection: CAD-4 EXPRESS (Enraf–Nonius, 1994 ▶); cell refinement: CAD-4 EXPRESS; data reduction: XCAD4 (Harms & Wocadlo, 1996 ▶); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008 ▶); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008 ▶); molecular graphics: PLATON (Spek, 2009 ▶); software used to prepare material for publication: SHELXL97.

Crystal structure: contains datablocks global, I. DOI: 10.1107/S160053680905541X/ci2998sup1.cif

Structure factors: contains datablocks I. DOI: 10.1107/S160053680905541X/ci2998Isup2.hkl

Additional supplementary materials: crystallographic information; 3D view; checkCIF report

C11H15NO2	F(000) = 416
Mr = 193.24	Dx = 1.195 Mg m−3
Monoclinic, P21/a	Mo Kα radiation, λ = 0.71073 Å
Hall symbol: -P 2yab	Cell parameters from 25 reflections
a = 12.6949 (8) Å	θ = 2–25°
b = 6.6596 (4) Å	µ = 0.08 mm−1
c = 12.8529 (9) Å	T = 293 K
β = 98.672 (11)°	Block, colourless
V = 1074.20 (12) Å3	0.18 × 0.15 × 0.13 mm
Z = 4

Nonius MACH-3 diffractometer	1424 reflections with I > 2σ(I)
Radiation source: fine-focus sealed tube	Rint = 0.051
graphite	θmax = 25.0°, θmin = 3.2°
ω–2θ scans	h = −1→15
Absorption correction: ψ scan (North et al., 1968)	k = −7→7
Tmin = 0.985, Tmax = 0.989	l = −15→15
4088 measured reflections	3 standard reflections every 60 min
1873 independent reflections	intensity decay: none

Refinement on F2	Secondary atom site location: difference Fourier map
Least-squares matrix: full	Hydrogen site location: inferred from neighbouring sites
R[F2 > 2σ(F2)] = 0.043	H-atom parameters constrained
wR(F2) = 0.134	w = 1/[σ2(Fo2) + (0.0618P)2 + 0.2249P] where P = (Fo2 + 2Fc2)/3
S = 1.05	(Δ/σ)max = 0.001
1873 reflections	Δρmax = 0.16 e Å−3
131 parameters	Δρmin = −0.13 e Å−3
0 restraints	Extinction correction: SHELXL97 (Sheldrick, 2008), Fc*=kFc[1+0.001xFc2λ3/sin(2θ)]-1/4
Primary atom site location: structure-invariant direct methods	Extinction coefficient: 0.018 (3)

Geometry. All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes.

Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger.

	x	y	z	Uiso*/Ueq
O1	0.40072 (9)	0.08183 (18)	0.88044 (9)	0.0572 (4)
O2	0.54776 (10)	0.0855 (2)	0.80386 (11)	0.0707 (4)
C1	0.34843 (11)	−0.5441 (3)	0.66547 (12)	0.0469 (4)
C4	0.42325 (12)	−0.1813 (3)	0.76552 (12)	0.0461 (4)
N1	0.31326 (11)	−0.7203 (3)	0.61807 (13)	0.0627 (5)
C7	0.46496 (12)	0.0065 (3)	0.81690 (12)	0.0497 (4)
C3	0.32462 (12)	−0.2619 (3)	0.77847 (12)	0.0479 (4)
H3	0.2828	−0.1950	0.8208	0.057*
C6	0.44776 (12)	−0.4608 (3)	0.65238 (13)	0.0528 (5)
H6	0.4900	−0.5262	0.6098	0.063*
C2	0.28788 (12)	−0.4375 (3)	0.73023 (13)	0.0491 (4)
H2	0.2217	−0.4869	0.7405	0.059*
C5	0.48322 (12)	−0.2852 (3)	0.70133 (13)	0.0531 (5)
H5	0.5492	−0.2343	0.6913	0.064*
C8	0.43523 (14)	0.2641 (3)	0.93720 (13)	0.0574 (5)
H8A	0.4448	0.3713	0.8884	0.069*
H8B	0.5023	0.2419	0.9829	0.069*
C1A	0.37347 (16)	−0.8242 (3)	0.54815 (15)	0.0685 (5)
H1A1	0.3762	−0.7437	0.4867	0.103*
H1A2	0.3397	−0.9501	0.5277	0.103*
H1A3	0.4445	−0.8481	0.5835	0.103*
C2A	0.21248 (14)	−0.8068 (3)	0.63395 (17)	0.0690 (6)
H2A1	0.2090	−0.8138	0.7080	0.103*
H2A2	0.2062	−0.9395	0.6044	0.103*
H2A3	0.1553	−0.7247	0.6000	0.103*
C9	0.34993 (18)	0.3176 (3)	1.00051 (16)	0.0767 (6)
H9A	0.2835	0.3340	0.9545	0.115*
H9B	0.3683	0.4409	1.0376	0.115*
H9C	0.3431	0.2125	1.0502	0.115*

	U11	U22	U33	U12	U13	U23
O1	0.0615 (7)	0.0553 (8)	0.0586 (7)	−0.0047 (6)	0.0215 (6)	−0.0083 (6)
O2	0.0583 (7)	0.0663 (9)	0.0929 (10)	−0.0141 (7)	0.0289 (7)	−0.0111 (7)
C1	0.0436 (8)	0.0519 (10)	0.0451 (8)	0.0024 (7)	0.0062 (6)	0.0041 (7)
C4	0.0448 (8)	0.0495 (10)	0.0459 (8)	0.0027 (7)	0.0129 (7)	0.0052 (7)
N1	0.0543 (8)	0.0650 (11)	0.0710 (10)	−0.0081 (7)	0.0163 (7)	−0.0160 (8)
C7	0.0481 (8)	0.0529 (10)	0.0500 (9)	0.0034 (8)	0.0132 (7)	0.0061 (8)
C3	0.0465 (8)	0.0507 (10)	0.0500 (9)	0.0056 (7)	0.0186 (7)	0.0041 (7)
C6	0.0470 (8)	0.0591 (11)	0.0560 (10)	0.0024 (8)	0.0200 (7)	−0.0052 (8)
C2	0.0399 (8)	0.0560 (11)	0.0535 (9)	0.0010 (7)	0.0139 (7)	0.0055 (8)
C5	0.0431 (8)	0.0622 (12)	0.0578 (10)	−0.0045 (8)	0.0198 (7)	−0.0025 (8)
C8	0.0711 (11)	0.0483 (10)	0.0526 (10)	−0.0032 (9)	0.0089 (8)	−0.0005 (8)
C1A	0.0794 (13)	0.0657 (13)	0.0612 (11)	0.0003 (11)	0.0133 (9)	−0.0123 (10)
C2A	0.0613 (11)	0.0597 (12)	0.0851 (13)	−0.0125 (10)	0.0083 (9)	−0.0028 (10)
C9	0.0951 (15)	0.0653 (13)	0.0750 (13)	0.0003 (12)	0.0296 (11)	−0.0139 (11)

O1—C7	1.3361 (19)	C2—H2	0.9300
O1—C8	1.449 (2)	C5—H5	0.9300
O2—C7	1.2095 (19)	C8—C9	1.493 (2)
C1—N1	1.365 (2)	C8—H8A	0.9700
C1—C2	1.408 (2)	C8—H8B	0.9700
C1—C6	1.411 (2)	C1A—H1A1	0.9600
C4—C5	1.389 (2)	C1A—H1A2	0.9600
C4—C3	1.395 (2)	C1A—H1A3	0.9600
C4—C7	1.475 (3)	C2A—H2A1	0.9600
N1—C1A	1.442 (2)	C2A—H2A2	0.9600
N1—C2A	1.446 (2)	C2A—H2A3	0.9600
C3—C2	1.372 (2)	C9—H9A	0.9600
C3—H3	0.9300	C9—H9B	0.9600
C6—C5	1.372 (3)	C9—H9C	0.9600
C6—H6	0.9300
C7—O1—C8	117.15 (13)	O1—C8—C9	106.59 (14)
N1—C1—C2	121.76 (14)	O1—C8—H8A	110.4
N1—C1—C6	121.51 (14)	C9—C8—H8A	110.4
C2—C1—C6	116.73 (16)	O1—C8—H8B	110.4
C5—C4—C3	117.49 (16)	C9—C8—H8B	110.4
C5—C4—C7	119.76 (14)	H8A—C8—H8B	108.6
C3—C4—C7	122.75 (14)	N1—C1A—H1A1	109.5
C1—N1—C1A	121.48 (15)	N1—C1A—H1A2	109.5
C1—N1—C2A	121.10 (15)	H1A1—C1A—H1A2	109.5
C1A—N1—C2A	117.40 (16)	N1—C1A—H1A3	109.5
O2—C7—O1	123.00 (17)	H1A1—C1A—H1A3	109.5
O2—C7—C4	124.59 (15)	H1A2—C1A—H1A3	109.5
O1—C7—C4	112.41 (13)	N1—C2A—H2A1	109.5
C2—C3—C4	121.61 (15)	N1—C2A—H2A2	109.5
C2—C3—H3	119.2	H2A1—C2A—H2A2	109.5
C4—C3—H3	119.2	N1—C2A—H2A3	109.5
C5—C6—C1	121.20 (14)	H2A1—C2A—H2A3	109.5
C5—C6—H6	119.4	H2A2—C2A—H2A3	109.5
C1—C6—H6	119.4	C8—C9—H9A	109.5
C3—C2—C1	121.24 (15)	C8—C9—H9B	109.5
C3—C2—H2	119.4	H9A—C9—H9B	109.5
C1—C2—H2	119.4	C8—C9—H9C	109.5
C6—C5—C4	121.73 (15)	H9A—C9—H9C	109.5
C6—C5—H5	119.1	H9B—C9—H9C	109.5
C4—C5—H5	119.1
C2—C1—N1—C1A	177.23 (16)	C7—C4—C3—C2	−179.64 (15)
C6—C1—N1—C1A	−3.2 (3)	N1—C1—C6—C5	−179.15 (16)
C2—C1—N1—C2A	−1.0 (3)	C2—C1—C6—C5	0.5 (2)
C6—C1—N1—C2A	178.53 (16)	C4—C3—C2—C1	0.1 (2)
C8—O1—C7—O2	−1.5 (2)	N1—C1—C2—C3	179.19 (15)
C8—O1—C7—C4	178.51 (13)	C6—C1—C2—C3	−0.4 (2)
C5—C4—C7—O2	3.6 (3)	C1—C6—C5—C4	−0.2 (3)
C3—C4—C7—O2	−176.55 (16)	C3—C4—C5—C6	−0.2 (2)
C5—C4—C7—O1	−176.49 (14)	C7—C4—C5—C6	179.69 (15)
C3—C4—C7—O1	3.4 (2)	C7—O1—C8—C9	179.26 (15)
C5—C4—C3—C2	0.3 (2)

D—H···A	D—H	H···A	D···A	D—H···A
C2—H2···O2i	0.93	2.55	3.4682 (19)	168

Table 1

Hydrogen-bond geometry (Å, °)

D—H⋯A	D—H	H⋯A	D⋯A	D—H⋯A
C2—H2⋯O2i	0.93	2.55	3.4682 (19)	168

Symmetry code: (i) .