Literature DB >> 21576613

Surgical site infection in elective operations for colorectal cancer after the application of preventive measures.

Xavier Serra-Aracil1, María Isabel García-Domingo, David Parés, Eloi Espin-Basany, Sebastiano Biondo, Xavier Guirao, Carola Orrego, Antonio Sitges-Serra.   

Abstract

OBJECTIVES: To assess the prevalence of surgical site infection (SSI) after elective operations for colon and rectal cancer after the application of evidence-based preventive measures and to identify risk factors for SSI.
DESIGN: Prospective, observational, multicenter.
SETTING: Tertiary and community public hospitals in Catalonia, Spain. PATIENTS: Consecutive patients undergoing elective surgical resections for colon and rectal cancer during a 9-month period. MAIN OUTCOME MEASURES: The prevalence of SSI within 30 days after the operations and risk factors for SSI.
RESULTS: Data from 611 patients were documented: 383 patients underwent operations for colon cancer and 228 underwent operations for rectal cancer. Surgical site infection was observed in 89 (23.2%) colon cancer patients (superficial, 12.8%; deep, 2.1%; and organ/space, 8.4%) and in 63 (27.6%) rectal cancer patients (superficial, 13.6%; deep, 5.7%; and organ/space, 8.3%). For colon procedures, the following independent predictive factors were identified: for incisional SSI, open procedure vs laparoscopy; for organ/space SSI, hyperglycemia at 48 hours postoperatively (serum glucose level, >200 mg/dL), ostomy, and National Nosocomial Infection System index of 1 or more. In rectal procedures, no risk factors were identified for incisional SSI; hyperglycemia at 48 hours postoperatively (serum glucose level, >200 mg/dL) and temperature lower than 36°C at the time of surgical incision were associated with organ/space SSI.
CONCLUSION: The prevalence of SSI in elective colon and rectal operations remains high despite the application of evidence-based preventive measures.

Entities:  

Mesh:

Year:  2011        PMID: 21576613     DOI: 10.1001/archsurg.2011.90

Source DB:  PubMed          Journal:  Arch Surg        ISSN: 0004-0010


  27 in total

1.  Impact of perioperative probiotic treatment for surgical site infections in patients with colorectal cancer.

Authors:  Naoya Aisu; Shu Tanimura; Yuichi Yamashita; Kanefumi Yamashita; Kenji Maki; Yoichiro Yoshida; Takamitsu Sasaki; Shinsuke Takeno; Seiichiro Hoshino
Journal:  Exp Ther Med       Date:  2015-07-15       Impact factor: 2.447

2.  Risk factors for surgical site infection in Japanese patients with ulcerative colitis: a multicenter prospective study.

Authors:  Toshimitsu Araki; Yoshiki Okita; Motoi Uchino; Hiroki Ikeuchi; Iwao Sasaki; Yuji Funayama; Kouhei Fukushima; Kitarou Futami; Kiyoshi Maeda; Tsuneo Iiai; Michio Itabashi; Kazuo Hase; Satoshi Motoya; Atsuo Kitano; Tsunekazu Mizushima; Kotaro Maeda; Minako Kobayashi; Yasuhiko Mohri; Masato Kusunoki
Journal:  Surg Today       Date:  2013-12-12       Impact factor: 2.549

3.  Risk factors for incisional surgical site infections in elective surgery for colorectal cancer: focus on intraoperative meticulous wound management.

Authors:  Keita Itatsu; Gen Sugawara; Yuji Kaneoka; Takehito Kato; Eiji Takeuchi; Michio Kanai; Hiroshi Hasegawa; Toshiyuki Arai; Yukihiro Yokoyama; Masato Nagino
Journal:  Surg Today       Date:  2013-08-06       Impact factor: 2.549

4.  Postoperative intra-abdominal infection is an independent prognostic factor of disease-free survival and disease-specific survival in patients with stage II colon cancer.

Authors:  P Sánchez-Velázquez; M Pera; M Jiménez-Toscano; X Mayol; X Rogés; L Lorente; M Iglesias; M Gallén
Journal:  Clin Transl Oncol       Date:  2018-04-05       Impact factor: 3.405

5.  Differences in surgical site infection between laparoscopic colon and rectal surgeries: sub-analysis of a multicenter randomized controlled trial (Japan-Multinational Trial Organization PREV 07-01).

Authors:  Saori Goto; Suguru Hasegawa; Hiroaki Hata; Takashi Yamaguchi; Koya Hida; Ryuta Nishitai; Satoshi Yamanokuchi; Akinari Nomura; Takeharu Yamanaka; Yoshiharu Sakai
Journal:  Int J Colorectal Dis       Date:  2016-09-07       Impact factor: 2.571

6.  Risk of surgical site infection in older patients in a cohort survey: targets for quality improvement in antibiotic prophylaxis.

Authors:  Antonella Agodi; Annalisa Quattrocchi; Martina Barchitta; Veronica Adornetto; Aldo Cocuzza; Rosalia Latino; Giovanni Li Destri; Antonio Di Cataldo
Journal:  Int Surg       Date:  2015-03

Review 7.  Bundles Prevent Surgical Site Infections After Colorectal Surgery: Meta-analysis and Systematic Review.

Authors:  Aleksander Zywot; Christine S M Lau; H Stephen Fletcher; Subroto Paul
Journal:  J Gastrointest Surg       Date:  2017-06-15       Impact factor: 3.452

8.  Perioperative hyperglycemia: an unmet need within a surgical site infection bundle.

Authors:  M Gachabayov; A J Senagore; S K Abbas; S B Yelika; K You; R Bergamaschi
Journal:  Tech Coloproctol       Date:  2018-03-06       Impact factor: 3.781

9.  Efficacy of skin closure with subcuticular sutures for preventing wound infection after resection of colorectal cancer: a propensity score-matched analysis.

Authors:  Yusuke Yamaoka; Masataka Ikeda; Masakazu Ikenaga; Naotsugu Haraguchi; Masakazu Miyake; Kazuyoshi Yamamoto; Tadafumi Asaoka; Kazuhiro Nishikawa; Atsushi Miyamoto; Michihiko Miyazaki; Motohiro Hirao; Shoji Nakamori; Mitsugu Sekimoto
Journal:  Langenbecks Arch Surg       Date:  2015-10-02       Impact factor: 3.445

10.  Hyperglycemia 3 days after esophageal cancer surgery is associated with an increased risk of postoperative infection.

Authors:  Naoko Ito; Takeshi Iwaya; Kenichiro Ikeda; Yusuke Kimura; Yuji Akiyama; Masafumi Konosu; Kaoru Ishida; Hisataka Fujiwara; Koki Otsuka; Hiroyuki Nitta; Masahiro Kashiwaba; Keisuke Koeda; Satoshi Nishizuka; Masaru Mizuno; Akira Sasaki; Go Wakabayashi
Journal:  J Gastrointest Surg       Date:  2014-07-04       Impact factor: 3.452

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