Literature DB >> 2157635

The spin trapping of superoxide with M4PO (3,3,5,5-tetramethylpyrroline-N-oxide).

G R Buettner1, B E Britigan.   

Abstract

The spin trap 3,3,5,5-tetramethylpyrroline-N-oxide (M4PO) reacts with superoxide to produce a short-lived spin adduct (M4PO/.OOH, AN = 14.0 G, AH = 6.5 G) that decays by a first-order process (t1/2 approximately 35 s at pH 7.4). This short lifetime may limit its usefulness in studies of superoxide.

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Year:  1990        PMID: 2157635     DOI: 10.1016/0891-5849(90)90145-9

Source DB:  PubMed          Journal:  Free Radic Biol Med        ISSN: 0891-5849            Impact factor:   7.376


  2 in total

1.  Synthesis and evaluation of 13C-labeled 5-5-dimethyl-1-pyrroline-N-oxide aimed at in vivo detection of reactive oxygen species using hyperpolarized 13C-MRI.

Authors:  Keita Saito; Deepak Sail; Kazutoshi Yamamoto; Shingo Matsumoto; Burchelle Blackman; Shun Kishimoto; Jeffrey R Brender; Rolf E Swenson; James B Mitchell; Murali C Krishna
Journal:  Free Radic Biol Med       Date:  2018-11-22       Impact factor: 7.376

2.  Investigating the reactive oxygen species production of Rose Bengal and Merocyanine 540-loaded radioluminescent nanoparticles.

Authors:  Anne Nsubuga; Gabrielle A Mandl; John A Capobianco
Journal:  Nanoscale Adv       Date:  2021-02-17
  2 in total

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