Literature DB >> 2157601

Mediation of nitrous oxide analgesia in mice by spinal and supraspinal kappa-opioid receptors.

R M Quock1, J A Best, D C Chen, L K Vaughn, P S Portoghese, A E Takemori.   

Abstract

Exposure to nitrous oxide produced concentration-dependent analgesia in the mouse abdominal constriction test. Intracerebroventricular or intrathecal pretreatment with naltrexone or nor-binaltorphimine significantly reduced nitrous oxide analgesia. However, similar pretreatment with beta-funaltrexamine had no appreciable effect. These findings suggest that nitrous oxide analgesia involves spinal and supraspinal kappa-opioid receptors.

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Year:  1990        PMID: 2157601     DOI: 10.1016/0014-2999(90)90158-3

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  12 in total

1.  Involvement of spinal cord opioid mechanisms in the acute antinociceptive effect of hyperbaric oxygen in mice.

Authors:  Jacqueline H Heeman; Yangmiao Zhang; Donald Y Shirachi; Raymond M Quock
Journal:  Brain Res       Date:  2013-10-07       Impact factor: 3.252

2.  Involvement of a NO-cyclic GMP-PKG signaling pathway in nitrous oxide-induced antinociception in mice.

Authors:  Yao Zhang; Lindsay P Quock; Eunhee Chung; Yusuke Ohgami; Raymond M Quock
Journal:  Eur J Pharmacol       Date:  2011-01-14       Impact factor: 4.432

3.  Yohimbine and flumazenil: effect on nitrous oxide-induced suppression of dorsal horn neurons in cats.

Authors:  Takahiko Okuda; Katsutoshi Wakita; Norio Tsuchiya; Kazuki Hatsuoka; Yoshihisa Koga
Journal:  J Anesth       Date:  1997-09       Impact factor: 2.078

4.  Nitrous oxide-induced NO-dependent neuronal release of β-endorphin from the rat arcuate nucleus and periaqueductal gray.

Authors:  Yusuke Ohgami; Eunhee Chung; Raymond M Quock
Journal:  Brain Res       Date:  2010-11-06       Impact factor: 3.252

5.  Involvement of the kappa-opioid receptor in nitrous oxide-induced analgesia in mice.

Authors:  Tomohiro Koyama; Kazuhiko Fukuda
Journal:  J Anesth       Date:  2010-02-17       Impact factor: 2.078

Review 6.  Advances in understanding the actions of nitrous oxide.

Authors:  Dimitris E Emmanouil; Raymond M Quock
Journal:  Anesth Prog       Date:  2007

Review 7.  Neurobiology of nitrous oxide-induced antinociceptive effects.

Authors:  Masahiko Fujinaga; Mervyn Maze
Journal:  Mol Neurobiol       Date:  2002-04       Impact factor: 5.590

8.  Antagonism of the antinociceptive effect of nitrous oxide by inhibition of enzyme activity or expression of neuronal nitric oxide synthase in the mouse brain and spinal cord.

Authors:  Jessica Lack Cope; Eunhee Chung; Yusuke Ohgami; Raymond M Quock
Journal:  Eur J Pharmacol       Date:  2009-10-08       Impact factor: 4.432

9.  Benzodiazepine receptor mediation of behavioral effects of nitrous oxide in mice.

Authors:  R M Quock; D E Emmanouil; L K Vaughn; R J Pruhs
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

10.  Nitrous oxide anxiolytic effect in mice in the elevated plus maze: mediation by benzodiazepine receptors.

Authors:  D E Emmanouil; C H Johnson; R M Quock
Journal:  Psychopharmacology (Berl)       Date:  1994-06       Impact factor: 4.530

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