Literature DB >> 21575943

Quantitative analysis of DNA methylation of imprinted genes in single human blastocysts by pyrosequencing.

John Huntriss1, Kathryn Woodfine, Joanna E Huddleston, Adele Murrell, Anthony J Rutherford, Kay Elder, Amir Ali Khan, Karen Hemmings, Helen Picton.   

Abstract

We report the first quantitative assessment of DNA methylation for any gene in the human preimplantation embryo to reveal that imprints exist at KvDMR1, RB1, SNRPN, and GRB10 in the human blastocyst. For comparison, in two human embryonic stem cell lines, imprints were also observed at KvDMR1, SNRPN, GRB10, and other imprinted loci, whereas RB1 and MEG3 were hypermethylated.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21575943     DOI： 10.1016/j.fertnstert.2011.04.035

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  8 in total

1.  Mutations causing familial biparental hydatidiform mole implicate c6orf221 as a possible regulator of genomic imprinting in the human oocyte.

Authors:  David A Parry; Clare V Logan; Bruce E Hayward; Michael Shires; Hanène Landolsi; Christine Diggle; Ian Carr; Cécile Rittore; Isabelle Touitou; Laurent Philibert; Rosemary A Fisher; Masoumeh Fallahian; John D Huntriss; Helen M Picton; Saghira Malik; Graham R Taylor; Colin A Johnson; David T Bonthron; Eamonn G Sheridan
Journal:  Am J Hum Genet       Date:  2011-09-01       Impact factor: 11.025

2.  Variable imprinting of the MEST gene in human preimplantation embryos.

Authors:  John D Huntriss; Karen E Hemmings; Matthew Hinkins; Anthony J Rutherford; Roger G Sturmey; Kay Elder; Helen M Picton
Journal:  Eur J Hum Genet       Date:  2012-07-04       Impact factor: 4.246

3.  DNA methylation dynamics at imprinted genes during bovine pre-implantation embryo development.

Authors:  Alan M O'Doherty; David A Magee; Lynee C O'Shea; Niamh Forde; Marijke E Beltman; Solomon Mamo; Trudee Fair
Journal:  BMC Dev Biol       Date:  2015-03-10       Impact factor: 1.978

4.  Is there any effect on imprinted genes H19, PEG3, and SNRPN during AOA?

Authors:  Rong Liang; Fang Fang; Sen Li; Xi Chen; Xiaohong Zhang; Qun Lu
Journal:  Open Med (Wars)       Date:  2022-01-15

5.  Bisulfite profiling of the MGMT promoter and comparison with routine testing in glioblastoma diagnostics.

Authors:  Sascha Tierling; Wiebke M Jürgens-Wemheuer; Alea Leismann; Julia Becker-Kettern; Michael Scherer; Arne Wrede; David Breuskin; Steffi Urbschat; Christoph Sippl; Joachim Oertel; Walter J Schulz-Schaeffer; Jörn Walter
Journal:  Clin Epigenetics       Date:  2022-02-18       Impact factor: 6.551

6.  Global gene expression profiling of individual human oocytes and embryos demonstrates heterogeneity in early development.

Authors:  Lisa Shaw; Sharon F Sneddon; Leo Zeef; Susan J Kimber; Daniel R Brison
Journal:  PLoS One       Date:  2013-05-22       Impact factor: 3.240

7.  Deoxyribonucleic acid methylation profiling of single human blastocysts by methylated CpG-island amplification coupled with CpG-island microarray.

Authors:  John Huntriss; Karen Hemmings; Praveen Baskaran; Lee Hazelwood; Kay Elder; Carl Virtanen; David Miller; Helen M Picton
Journal:  Fertil Steril       Date:  2015-04-22       Impact factor: 7.329

8.  Methylation and transcripts expression at the imprinted GNAS locus in human embryonic and induced pluripotent stem cells and their derivatives.

Authors:  Virginie Grybek; Laetitia Aubry; Stéphanie Maupetit-Méhouas; Catherine Le Stunff; Cécile Denis; Mathilde Girard; Agnès Linglart; Caroline Silve
Journal:  Stem Cell Reports       Date:  2014-08-07       Impact factor: 7.765
  8 in total

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