Literature DB >> 21573924

Pharmaceuticals in the environment: an educational perspective.

Marco Eissen1, Donata Backhaus.   

Abstract

PURPOSE: Pharmaceuticals are an integral part of a dignified life. However, a lack of degradability and threats to the welfare of living beings cause concern due to their emission into the environment. There is also a lack of knowledge about cause and consequence. Therefore, we intend to contribute to the development of educational programmes which should increasingly include the topic 'pharmaceuticals in the environment'.
METHODS: Considering the current literature, we developed a corresponding series of worksheets (Online Resource) and sample solutions on an introductory level and integrated them into our curriculum.
RESULTS: The material compiled for the worksheets was arranged in a logical order and considers several subtopics. The worksheets aim to support the examination of related aspects such as environmental effects, emissions, wastewater treatment plants, degradation, degradation by-products, advanced oxidation processes, hydraulic retention times, half-life times, biosolids, exposition pathways, precautionary principle, classification schemes for pharmaceuticals and, related to the structure-activity relationship, the design for degradability. The students managed to work on the tasks in an appropriate manner and received a good overview of the occurrence and fate of pharmaceuticals in the environment.
CONCLUSIONS: Tasks that were presented to students regarding the topic 'pharmaceuticals in the environment' contributed to a better understanding of the possible risks of medical care on an introductory level. The tasks have been incorporated into a logic series of worksheets (Online Resource) with sample solutions available. Alternatively, the material would be appropriate for the preparation of a corresponding lecture on this topic.

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Year:  2011        PMID: 21573924     DOI: 10.1007/s11356-011-0512-6

Source DB:  PubMed          Journal:  Environ Sci Pollut Res Int        ISSN: 0944-1344            Impact factor:   4.223


  61 in total

Review 1.  Xenobiotics in the environment: present and future strategies to obviate the problem of biological persistence.

Authors:  Paul Gerhard Rieger; Helmut Martin Meier; Michael Gerle; Uwe Vogt; Torsten Groth; Hans Joachim Knackmuss
Journal:  J Biotechnol       Date:  2002-03-14       Impact factor: 3.307

2.  Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data.

Authors:  Thomas Heberer
Journal:  Toxicol Lett       Date:  2002-05-10       Impact factor: 4.372

Review 3.  Designing small molecules for biodegradability.

Authors:  R S Boethling; Elizabeth Sommer; David DiFiore
Journal:  Chem Rev       Date:  2007-05-27       Impact factor: 60.622

4.  Opening the "green pharmacy".

Authors:  Naomi Lubick
Journal:  Environ Sci Technol       Date:  2008-12-01       Impact factor: 9.028

Review 5.  Alternative solvent-free methodologies in the synthesis of pharmaceutical drugs.

Authors:  William C Shearouse; Daniel C Waddell; James Mack
Journal:  Curr Opin Drug Discov Devel       Date:  2009-11

Review 6.  Occurrence and fate of human pharmaceuticals in the environment.

Authors:  Sara C Monteiro; Alistair B A Boxall
Journal:  Rev Environ Contam Toxicol       Date:  2010       Impact factor: 7.563

7.  Persistence of estrogenic hormones in agricultural soils: II. 17Alpha-ethynylestradiol.

Authors:  M S Colucci; E Topp
Journal:  J Environ Qual       Date:  2001 Nov-Dec       Impact factor: 2.751

8.  Fe(III)-solar light induced degradation of diethyl phthalate (DEP) in aqueous solutions.

Authors:  G Mailhot; M Sarakha; B Lavedrine; J Cáceres; S Malato
Journal:  Chemosphere       Date:  2002-11       Impact factor: 7.086

9.  Collapse of a fish population after exposure to a synthetic estrogen.

Authors:  Karen A Kidd; Paul J Blanchfield; Kenneth H Mills; Vince P Palace; Robert E Evans; James M Lazorchak; Robert W Flick
Journal:  Proc Natl Acad Sci U S A       Date:  2007-05-21       Impact factor: 11.205

Review 10.  Review of the occurrence of anti-infectives in contaminated wastewaters and natural and drinking waters.

Authors:  Pedro A Segura; Matthieu François; Christian Gagnon; Sébastien Sauvé
Journal:  Environ Health Perspect       Date:  2009-01-22       Impact factor: 9.031

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  2 in total

Review 1.  Green pharmacy - a narrative review.

Authors:  Alexandra Toma; Ofelia Crişan
Journal:  Clujul Med       Date:  2018-10-30

2.  Consumer-perceived risks and choices about pharmaceuticals in the environment: a cross-sectional study.

Authors:  Simone Dohle; Victoria E A Campbell; Joseph L Arvai
Journal:  Environ Health       Date:  2013-06-05       Impact factor: 5.984

  2 in total

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