| Literature DB >> 21570749 |
Xizhen Jiang1, Wenlu Liu, Wei Zhang, Faqin Jiang, Zhe Gao, Hao Zhuang, Lei Fu.
Abstract
Thirteen compounds, based on benzofuran skeleton bearing aryl substituents at its C-3 position through methanone linker, were synthesized and screened for their antibacterial and antifungal activities against four bacteria Escherichia coli, Staphylococcus aureus, Methicillin-resistant S.aureus, Bacillus subtilis, and a fungus Candida albicans. Four hydrophobic benzofuran analogs were found to exhibit favorable antibacterial activities (MIC(80) = 0.39-3.12 μg/mL), which were better than the control drugs.Entities:
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Year: 2011 PMID： 21570749 DOI： 10.1016/j.ejmech.2011.04.053
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514