Literature DB >> 21570198

Asthma and suicide: possible role of brain-derived neurotrophic factor.

Esra Ozek1, Barış Ekici.   

Abstract

The suicide rates among asthmatic patients are higher than among the general population. Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family and is strongly associated with suicide pathogenesis. BDNF also plays an important role in neuroimmune reactions in allergic diseases such as asthma. Therefore, we hypothesize that alterations of BDNF levels in the brain may explain the increased suicide rates among asthmatic patients.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21570198     DOI: 10.1016/j.mehy.2011.04.028

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  2 in total

1.  Identifying rare variants for genetic risk through a combined pedigree and phenotype approach: application to suicide and asthma.

Authors:  T M Darlington; R Pimentel; K Smith; A V Bakian; L Jerominski; J Cardon; N J Camp; W B Callor; T Grey; M Singleton; M Yandell; P F Renshaw; D A Yurgelun-Todd; D Gray; H Coon
Journal:  Transl Psychiatry       Date:  2014-10-21       Impact factor: 6.222

2.  Correlation of 5-HTT, BDNF and NPSR1 gene polymorphisms with anxiety and depression in asthmatic patients.

Authors:  Yuan Yang; Mingzhe Zhao; Yuqun Zhang; Xinhua Shen; Yonggui Yuan
Journal:  Int J Mol Med       Date:  2016-05-09       Impact factor: 4.101

  2 in total

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