J Lu1, R F Bu2, Z L Sun3, Q S Lu1, H Jin1, Y Wang1, S H Wang1, L Li1, Z L Xie1, B Q Yang1. 1. Institute of Diabetes, Zhongda Hospital, Medical School, Southeast University, Nanjing, China. 2. Department of Endocrinology and Metabolism, Wuxi People's Hospital, Wuxi, China. 3. Institute of Diabetes, Zhongda Hospital, Medical School, Southeast University, Nanjing, China. Electronic address: sunzilin1963@yahoo.com.cn.
Abstract
AIM: To assess whether self-monitoring of quantitative urine glucose or blood glucose is effective, convenient and safe for glycaemic control in non-insulin treated type 2 diabetes. METHODS:Adults with non-insulin treated type 2 diabetes were recruited and randomized into three groups: Group A, self-monitoring with a quantitative urine glucose meter (n = 38); Group B, self monitoring with a blood glucose meter (n=35); Group C, the control group without self monitoring (n=35). All patients were followed up for six months, during which identical diabetes care was provided. RESULTS: There was a significant decrease in HbA1c within each group (p < 0.05). At the study conclusion, mean changes in HbA1c from baseline were -1.9% for Group A, -1.5% for Group B and -1.0% for Group C, and the proportion of patients achieving HbA1c ≤ 6.5% were 38.9%, 35.3% and 20.0% respectively. However, no significant differences between the groups were found. The average monitoring frequency was significantly higher in Group A than in Group B. The incidence of hypoglycaemia and quality of life scores were similar between the groups. CONCLUSIONS: This study suggests that self-monitoring of urine glucose has comparable efficacy on glycaemic control, and facilitates better compliance than blood self monitoring, without influencing the quality of life or risk of hypoglycaemia.
RCT Entities:
AIM: To assess whether self-monitoring of quantitative urine glucose or blood glucose is effective, convenient and safe for glycaemic control in non-insulin treated type 2 diabetes. METHODS: Adults with non-insulin treated type 2 diabetes were recruited and randomized into three groups: Group A, self-monitoring with a quantitative urine glucose meter (n = 38); Group B, self monitoring with a blood glucose meter (n=35); Group C, the control group without self monitoring (n=35). All patients were followed up for six months, during which identical diabetes care was provided. RESULTS: There was a significant decrease in HbA1c within each group (p < 0.05). At the study conclusion, mean changes in HbA1c from baseline were -1.9% for Group A, -1.5% for Group B and -1.0% for Group C, and the proportion of patients achieving HbA1c ≤ 6.5% were 38.9%, 35.3% and 20.0% respectively. However, no significant differences between the groups were found. The average monitoring frequency was significantly higher in Group A than in Group B. The incidence of hypoglycaemia and quality of life scores were similar between the groups. CONCLUSIONS: This study suggests that self-monitoring of urine glucose has comparable efficacy on glycaemic control, and facilitates better compliance than blood self monitoring, without influencing the quality of life or risk of hypoglycaemia.
Authors: Shari D Bolen; Apoorva Chandar; Corinna Falck-Ytter; Carl Tyler; Adam T Perzynski; Alida M Gertz; Paulette Sage; Steven Lewis; Maurine Cobabe; Ying Ye; Michelle Menegay; Donna M Windish Journal: J Gen Intern Med Date: 2014-04-15 Impact factor: 5.128
Authors: Juan Chen; Hai Jian Guo; Shan-Hu Qiu; Wei Li; Xiao-Hang Wang; Min Cai; Bei Wang; Xiao-Ning Li; Zi-Lin Sun Journal: Chin Med J (Engl) Date: 2018-07-20 Impact factor: 2.628