Literature DB >> 21568914

Recent developments in the synthesis and biological activity of muramylpeptides.

K Dzierzbicka1, A Wardowska, P Trzonkowski.   

Abstract

Derivatives of muramyl dipeptide (MDP) are considered as immunostimulants and adjuvants in the immunotherapy of cancer and infections. The interest in these compounds is mainly related to a high variety of their structure and biological properties. Here, we describe the synthesis and biological activity of several recently developed classes of MDP analogues. We also report potential of these analogues in the treatment of cancer and infectious diseases in experimental systems and cancer patients.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21568914     DOI： 10.2174/092986711795843173

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN： 0929-8673            Impact factor:   4.530


  8 in total

Review 1.  Messenger functions of the bacterial cell wall-derived muropeptides.

Authors:  Marc A Boudreau; Jed F Fisher; Shahriar Mobashery
Journal:  Biochemistry       Date:  2012-03-27       Impact factor: 3.162

2.  Molecular adjuvants based on nonpyrogenic lipophilic derivatives of norAbuMDP/GMDP formulated in nanoliposomes: stimulation of innate and adaptive immunity.

Authors:  Pavlína Turánek Knotigová; Daniel Zyka; Josef Mašek; Anna Kovalová; Michal Křupka; Eliška Bartheldyová; Pavel Kulich; Štěpán Koudelka; Róbert Lukáč; Zuzana Kauerová; Antonín Vacek; Milada Stuchlová Horynová; Alois Kozubík; Andrew D Miller; Ladislav Fekete; Irena Kratochvílová; Jan Ježek; Miroslav Ledvina; Milan Raška; Jaroslav Turánek
Journal:  Pharm Res       Date:  2015-01-30       Impact factor: 4.200

Review 3.  Developments in Vaccine Adjuvants.

Authors:  Farrhana Ziana Firdaus; Mariusz Skwarczynski; Istvan Toth
Journal:  Methods Mol Biol       Date:  2022

4.  Muramyl dipeptide induces NOD2-dependent Ly6C(high) monocyte recruitment to the lungs and protects against influenza virus infection.

Authors:  François Coulombe; Stéphanie Fiola; Shizuo Akira; Yvon Cormier; Jean Gosselin
Journal:  PLoS One       Date:  2012-05-09       Impact factor: 3.240

Review 5.  Adjuvants: Classification, Modus Operandi, and Licensing.

Authors:  Juliana de Souza Apostólico; Victória Alves Santos Lunardelli; Fernanda Caroline Coirada; Silvia Beatriz Boscardin; Daniela Santoro Rosa
Journal:  J Immunol Res       Date:  2016-05-04       Impact factor: 4.818

Review 6.  Muramyl dipeptide-based analogs as potential anticancer compounds: Strategies to improve selectivity, biocompatibility, and efficiency.

Authors:  Eliza Iwicka; Justyna Hajtuch; Krystyna Dzierzbicka; Iwona Inkielewicz-Stepniak
Journal:  Front Oncol       Date:  2022-09-27       Impact factor: 5.738

7.  Investigation of chemical transformations of thiophenylglycoside of muramyl dipeptide on the fumed silica surface using TPD-MS, FTIR spectroscopy and ES IT MS.

Authors:  Liana R Azizova; Tetiana V Kulik; Borys B Palianytsia; Aleksandr E Zemlyakov; Viktoriya N Tsikalova; Vasiliy Ya Chirva
Journal:  Nanoscale Res Lett       Date:  2014-05-13       Impact factor: 4.703

8.  Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid.

Authors:  Agnieszka Siebert; Magdalena Wysocka; Beata Krawczyk; Grzegorz Cholewiński; Janusz Rachoń
Journal:  Eur J Med Chem       Date:  2017-12-01       Impact factor: 6.514
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.