Literature DB >> 21567260

Alterations in pelvic floor muscles and pelvic organ support by pregnancy and vaginal delivery in squirrel monkeys.

Jessica N Bracken1, Michelle Reyes, Jilene M Gendron, Lisa M Pierce, Val M Runge, Thomas J Kuehl.   

Abstract

INTRODUCTION AND HYPOTHESIS: The objective of this study was to measure the effects of pregnancy and parturition on pelvic floor muscles and pelvic organ support.
METHODS: Levator ani, obturator internus, and coccygeus (COC) muscle volumes and contrast uptake were assessed by MRI of seven females prior to pregnancy, 3 days, and 4 months postpartum. Bladder neck and cervix position were measured dynamically with abdominal squeezing.
RESULTS: The sides of three paired muscles were similar (p > 0.66). COC volumes were greater (p < 0.004) after parturition than before pregnancy or after recovery. COC contrast uptake increased (p < 0.02) immediately after delivery. Bladder neck position both in the relaxed state and abdominal pressure descended (p < 0.04) after delivery and descended further (p < 0.001) after recovery. Cervical position in the relaxed state before delivery was higher (p < 0.001) than postpartum but was unchanged (p = 0.50) with abdominal pressure relative to delivery.
CONCLUSION: In squirrel monkeys, coccygeus muscles demonstrate the greatest change related to parturition, and parturition-related bladder neck descent seems permanent.

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Year:  2011        PMID: 21567260      PMCID: PMC4128415          DOI: 10.1007/s00192-011-1443-y

Source DB:  PubMed          Journal:  Int Urogynecol J        ISSN: 0937-3462            Impact factor:   2.894


  21 in total

1.  MR-based three-dimensional modeling of the normal pelvic floor in women: quantification of muscle mass.

Authors:  J R Fielding; H Dumanli; A G Schreyer; S Okuda; D T Gering; K H Zou; R Kikinis; F A Jolesz
Journal:  AJR Am J Roentgenol       Date:  2000-03       Impact factor: 3.959

2.  The appearance of levator ani muscle abnormalities in magnetic resonance images after vaginal delivery.

Authors:  John O L DeLancey; Rohna Kearney; Queena Chou; Steven Speights; Shereen Binno
Journal:  Obstet Gynecol       Date:  2003-01       Impact factor: 7.661

3.  Dynamic assessment of pelvic floor and bony pelvis morphologic condition with the use of magnetic resonance imaging in a multiethnic, nulliparous, and healthy female population.

Authors:  Diaa E E Rizk; Janusz Czechowski; Leif Ekelund
Journal:  Am J Obstet Gynecol       Date:  2004-07       Impact factor: 8.661

4.  Levator ani thickness variations in symptomatic and asymptomatic women using magnetic resonance-based 3-dimensional color mapping.

Authors:  Lennox Hoyte; Marianna Jakab; Simon K Warfield; Susan Shott; George Flesh; Julia R Fielding
Journal:  Am J Obstet Gynecol       Date:  2004-09       Impact factor: 8.661

Review 5.  Vaginal delivery and pelvic floor dysfunction: current evidence and implications for future research.

Authors:  M A T Bortolini; H P Drutz; D Lovatsis; M Alarab
Journal:  Int Urogynecol J       Date:  2010-05-06       Impact factor: 2.894

6.  Two- and 3-dimensional MRI comparison of levator ani structure, volume, and integrity in women with stress incontinence and prolapse.

Authors:  L Hoyte; L Schierlitz; K Zou; G Flesh; J R Fielding
Journal:  Am J Obstet Gynecol       Date:  2001-07       Impact factor: 8.661

7.  [Functional MRI of the pelvic floor: postpartum changes of primiparous women after spontaneous vaginal delivery].

Authors:  A Lienemann; T Fischer; C Anthuber; M Reiser
Journal:  Rofo       Date:  2003-08

8.  Innervation of the levator ani muscles in the female squirrel monkey.

Authors:  Lisa M Pierce; Michelle Reyes; Karl B Thor; Paul C Dolber; Ronald E Bremer; Thomas J Kuehl; Kimberly W Coates
Journal:  Am J Obstet Gynecol       Date:  2003-05       Impact factor: 8.661

9.  The squirrel monkey: an animal model of pelvic relaxation.

Authors:  K W Coates; H L Galan; B L Shull; T J Kuehl
Journal:  Am J Obstet Gynecol       Date:  1995-02       Impact factor: 8.661

10.  The squirrel monkey as an animal model of pelvic relaxation: an evaluation of a large breeding colony.

Authors:  K W Coates; S Gibson; L E Williams; A Brady; C R Abee; B L Shull; T J Kuehl
Journal:  Am J Obstet Gynecol       Date:  1995-12       Impact factor: 8.661

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  4 in total

1.  Randomized trial of cesarean vs vaginal delivery for effects on the pelvic floor in squirrel monkeys.

Authors:  Fiona M Lindo; Emily S Carr; Michelle Reyes; Jilene M Gendron; Julio C Ruiz; Virginia L Parks; Thomas J Kuehl; Wilma I Larsen
Journal:  Am J Obstet Gynecol       Date:  2015-09-12       Impact factor: 8.661

2.  Comparison of pelvic muscle architecture between humans and commonly used laboratory species.

Authors:  Marianna Alperin; Lori J Tuttle; Blair R Conner; Danielle M Dixon; Margie A Mathewson; Samuel R Ward; Richard L Lieber
Journal:  Int Urogynecol J       Date:  2014-06-11       Impact factor: 2.894

3.  Lack of association between pelvic outlet diameter and pelvic organ prolapse in squirrel monkeys.

Authors:  John S Joyce; Sarah Dornak; Jilene M Gendron; Michelle Reyes; Julio C Ruiz; Thomas J Kuehl
Journal:  Int Urogynecol J       Date:  2014-03-20       Impact factor: 2.894

4.  Animal models for pelvic organ prolapse: systematic review.

Authors:  Marina Gabriela M C Mori da Cunha; Katerina Mackova; Lucie Hajkova Hympanova; Maria Augusta T Bortolini; Jan Deprest
Journal:  Int Urogynecol J       Date:  2021-01-23       Impact factor: 2.894

  4 in total

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