| Literature DB >> 2156505 |
E Vignon1, P Broquet, P Mathieu, P Louisot, M Richard.
Abstract
Using radioligand binding assays, histaminergic H1, serotoninergic, dopaminergic and Beta adrenergic receptors were studied in human normal and osteoarthritic cartilage. The four studied receptors were present in normal cartilage; serotoninergic, dopaminergic and Beta adrenergic receptors were significantly increased in osteoarthritic cartilage while histaminergic H1 receptors were significantly increased only in osteophytic cartilage. The results are consistent with a non specific activation of osteoarthritic chondrocytes.Entities:
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Year: 1990 PMID： 2156505
Source DB: PubMed Journal: Biochem Int ISSN： 0158-5231