| Literature DB >> 2156489 |
A G Bukrinskaya1, N K Sharova.
Abstract
The treatment of HIV-1 virions with ionic and nonionic detergents (NP 40, octylglucoside, Na deoxycholate) resulted in an effect unusual for enveloped viruses: instead of solubilization of glycoproteins, the core protein p24 was solubilized while envelope glycoproteins with other structural proteins were found in subviral particles. These data are consistent with a model of HIV structural organization in which glycoproteins are included in the matrix formed by the protein p 17 and suggest that p24 is neither involved in the matrix nor closely bound to any viral proteins.Entities:
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Year: 1990 PMID: 2156489 DOI: 10.1007/BF01311297
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574