Literature DB >> 21563729

Incidence and characteristics of unilateral keratoconus classified on corneal topography.

Rui Hua Wei1, Shao Zhen Zhao, Li Lim, Donald T H Tan.   

Abstract

PURPOSE: To evaluate the characteristics of unilateral keratoconus defined on the basis of corneal topography and analyze videokeratography parameters between fellow eyes and normal controls.
METHODS: A total of 111 patients with clinical keratoconus were prospectively enrolled. Both eyes were evaluated with Tomey (Tomey Corp) and Orbscan II (Bausch & Lomb) corneal topography systems. The patient was classified as having unilateral keratoconus if one eye had clinical keratoconus and the other eye did not have any topographic signs of keratoconus such as asymmetric videokeratographic pattern, positive result in Tomey keratoconus screening, maximum posterior elevation >40 μm, or corneal thinnest pachymetry <500 μm. Clinical characteristics and 13 Orbscan II quantitative indices between keratoconic and fellow eyes and normal control eyes were evaluated.
RESULTS: Five (4.5%) of 111 patients with keratoconus had no topographic evidence of keratoconus in the fellow eye. All clinically normal fellow eyes had symmetric bowtie patterns. Statistically significant differences were noted in maximum posterior elevation, corneal irregularity, and corneal thinnest values between keratoconic eyes and fellow eyes, and between keratoconic eyes and control eyes. Only 3-mm irregularity was significantly higher in the fellow eyes compared with control eyes (P<.05). An increased trend for corneal 5-mm irregularity was found in fellow eyes compared to control eyes.
CONCLUSIONS: The incidence of unilateral keratoconus was 4.5%. A trend of higher irregularity was found in fellow eyes compared with control eyes. This finding indicates that fellow eyes may show a certain low-expressivity morphologic feature of keratoconus. Copyright 2011, SLACK Incorporated.

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Mesh:

Year:  2011        PMID: 21563729     DOI: 10.3928/1081597X-20110426-01

Source DB:  PubMed          Journal:  J Refract Surg        ISSN: 1081-597X            Impact factor:   3.573


  10 in total

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2.  Topographic typology in a consecutive series of refractive surgery candidates.

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3.  Topographic characteristics of keratoconus among a sample of Jordanian patients.

Authors:  Mohammed Ali Abu Ameerh; Nathalie Bussières; Ghada Ismail Hamad; Muawyah Dawoud Al Bdour
Journal:  Int J Ophthalmol       Date:  2014-08-18       Impact factor: 1.779

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Journal:  Biomed Res Int       Date:  2015-05-17       Impact factor: 3.411

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7.  Topography and Higher Order Corneal Aberrations of the Fellow Eye in Unilateral Keratoconus.

Authors:  Mustafa Koç; Kemal Tekin
Journal:  Turk J Ophthalmol       Date:  2018-10-31

8.  Evaluation of Scheimpflug Tomography Parameters in Subclinical Keratoconus, Clinical Keratoconus and Normal Caucasian Eyes.

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Journal:  Turk J Ophthalmol       Date:  2018-06-28

9.  Topography and Higher Order Corneal Aberrations of the Fellow Eye in Unilateral Keratoconus.

Authors:  Sibel Aksoy; Sezen Akkaya; Yelda Özkurt; Sevda Kurna; Banu Açıkalın; Tomris Şengör
Journal:  Turk J Ophthalmol       Date:  2017-10-27

10.  Comparative analysis of the morphological and biomechanical properties of normal cornea and keratoconus at different stages.

Authors:  Ying Wu; Li-Li Guo; Lei Tian; Ze-Quan Xu; Qian Li; Jian Hu; Yi-Fei Huang; Li-Qiang Wang
Journal:  Int Ophthalmol       Date:  2021-07-07       Impact factor: 2.031

  10 in total

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