Literature DB >> 21563281

The natural product cyclomarin kills Mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease.

Esther K Schmitt1, Meliana Riwanto, Vasan Sambandamurthy, Silvio Roggo, Charlotte Miault, Christian Zwingelstein, Philipp Krastel, Christian Noble, David Beer, Srinivasa P S Rao, Melvin Au, Pornwaratt Niyomrattanakit, Viviam Lim, Jun Zheng, Douglas Jeffery, Kevin Pethe, Luis R Camacho.   

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Year:  2011        PMID： 21563281     DOI： 10.1002/anie.201101740

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  55 in total

Review 1.  Natural products as probes in pharmaceutical research.

Authors:  Esther K Schmitt; D Hoepfner; P Krastel
Journal:  J Ind Microbiol Biotechnol       Date:  2015-10-05       Impact factor: 3.346

2.  Lassomycin, a ribosomally synthesized cyclic peptide, kills mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2.

Authors:  Ekaterina Gavrish; Clarissa S Sit; Shugeng Cao; Olga Kandror; Amy Spoering; Aaron Peoples; Losee Ling; Ashley Fetterman; Dallas Hughes; Anthony Bissell; Heather Torrey; Tatos Akopian; Andreas Mueller; Slava Epstein; Alfred Goldberg; Jon Clardy; Kim Lewis
Journal:  Chem Biol       Date:  2014-03-27

3.  Structural basis of mycobacterial inhibition by cyclomarin A.

Authors:  Dileep Vasudevan; Srinivasa P S Rao; Christian G Noble
Journal:  J Biol Chem       Date:  2013-09-10       Impact factor: 5.157

4.  The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring.

Authors:  Tatos Akopian; Olga Kandror; Ravikiran M Raju; Meera Unnikrishnan; Eric J Rubin; Alfred L Goldberg
Journal:  EMBO J       Date:  2012-01-27       Impact factor: 11.598

5.  para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis.

Authors:  Jun Zheng; Eric J Rubin; Pablo Bifani; Vanessa Mathys; Vivian Lim; Melvin Au; Jichan Jang; Jiyoun Nam; Thomas Dick; John R Walker; Kevin Pethe; Luis R Camacho
Journal:  J Biol Chem       Date:  2013-06-18       Impact factor: 5.157

Review 6.  New antituberculous drugs derived from natural products: current perspectives and issues in antituberculous drug development.

Authors:  Masayuki Igarashi; Yoshimasa Ishizaki; Yoshiaki Takahashi
Journal:  J Antibiot (Tokyo)       Date:  2017-11-01       Impact factor: 2.649

7.  Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease.

Authors:  Kirsten Famulla; Peter Sass; Imran Malik; Tatos Akopian; Olga Kandror; Marina Alber; Berthold Hinzen; Helga Ruebsamen-Schaeff; Rainer Kalscheuer; Alfred L Goldberg; Heike Brötz-Oesterhelt
Journal:  Mol Microbiol       Date:  2016-04-01       Impact factor: 3.501

8.  Asymmetric copper-catalyzed C-N cross-couplings induced by visible light.

Authors:  Quirin M Kainz; Carson D Matier; Agnieszka Bartoszewicz; Susan L Zultanski; Jonas C Peters; Gregory C Fu
Journal:  Science       Date:  2016-02-12       Impact factor: 47.728

Review 9.  The tuberculosis drug discovery and development pipeline and emerging drug targets.

Authors:  Khisimuzi Mdluli; Takushi Kaneko; Anna Upton
Journal:  Cold Spring Harb Perspect Med       Date:  2015-01-29       Impact factor: 6.915

10.  Antibacterial activity of and resistance to small molecule inhibitors of the ClpP peptidase.

Authors:  Corey L Compton; Karl R Schmitz; Robert T Sauer; Jason K Sello
Journal:  ACS Chem Biol       Date:  2013-10-04       Impact factor: 5.100
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