| Literature DB >> 21559940 |
Hui-Chun Huang1, Yu-Chin Wu, Lee-Yung Shih, Woei-Chung Lo, Chon-Haw Tsai, Woei-Cherng Shyu.
Abstract
We report a case of polycythemia vera with chorea in which the brain metabolism and dopamine system were investigated using 2-[(18)F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET) and (99m)Tc-labeled tropane dopamine transporter ((99m)Tc-TRODAT-1) single photon emission computed tomography (SPECT). Along with normalization of the hematocrit and clinical symptoms after consecutive phlebotomies, the FDG PET scan and (99m)Tc-TRODAT-1 SPECT images returned towards normal. It is hypothesized that the development of polycythemia chorea is associated with a reversible alteration in the corticobasal ganglia metabolism and disturbed dopaminergic function.Entities:
Mesh:
Year: 2011 PMID: 21559940 DOI: 10.1007/s00415-011-6069-y
Source DB: PubMed Journal: J Neurol ISSN: 0340-5354 Impact factor: 4.849