Literature DB >> 21559769

Andersson lesion: are we misdiagnosing it? A retrospective study of clinico-radiological features and outcome of short segment fixation.

Bharat R Dave1, Himanshu Ram, Ajay Krishnan.   

Abstract

This study reviews the presentation, etiology, imaging characteristics and reasons for missed diagnosis of Andersson lesion (AL) and analyzes the surgical results of short segment fixation in the thoracolumbar region. This is a retrospective single center study. Fourteen patients (15 lesions) who were operated for AL were analyzed. The study was designed in two parts. The first part consisted of analysis of clinical and radiological features (MRI and radiographs) to highlight, whether definitive characteristics exist. The second part consisted of analysis of outcome of short segment fixation as measured by VAS, Frankel score, AsQoL index, and union, with assessment of complications. The follow-up was 42.33 ± 19.29 months (13 males and 1 female) with a mean age of 61.13 ± 19.74 years. There was predisposing trauma in five patients. There was a delay in presentation of the patients by 5.86 ± 2.50 months. There was misdiagnosis in all the cases, at primary orthopedic level (ten cases were put on anti-tuberculous treatment due to its MRI resemblance to infection) and all but one case at radiologist level. Radiographs and MRI had characteristic features in all cases, and MRI could detect posterior element affection in 14 lesions as against only 8 posterior lesions detected in radiographs. In all patients, there was a patient's delay and/or physician's delay to arrive at a diagnosis. Spinal fusion was seen in all the cases. Outcome measures of VAS, Frankel score, and AsQoL index showed significant improvement (P < 0.002). No major complications occurred. There is a lack of awareness of AL leading to misdiagnosis. Definite clinico-radiological features do exist in AL and short segment fixation is effective.

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Year:  2011        PMID: 21559769      PMCID: PMC3175887          DOI: 10.1007/s00586-011-1836-0

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  29 in total

1.  Spinal fractures and pseudoarthrosis complicating ankylosing spondylitis: MRI manifestation and clinical significance.

Authors:  T T Shih; P Q Chen; Y W Li; C Y Hsu
Journal:  J Comput Assist Tomogr       Date:  2001 Mar-Apr       Impact factor: 1.826

2.  [Surgical treatment of spondylodiscitis in ankylosing spondylitis. Two cases report].

Authors:  M Escosa Bagé; E García Navarrete; J M Pascual Garvi; R G Sola
Journal:  Rev Neurol       Date:  2001 Nov 16-30       Impact factor: 0.870

3.  Posterior correction and fixation without anterior fusion for pseudoarthrosis with kyphotic deformity in ankylosing spondylitis.

Authors:  Kao-Wha Chang; Min-Yu Tu; Hsin-Hsiung Huang; Hung-Chang Chen; Ying-Yu Chen; Chien-Chung Lin
Journal:  Spine (Phila Pa 1976)       Date:  2006-06-01       Impact factor: 3.468

4.  Multiple and simultaneous spine fractures in ankylosing spondylitis: case report.

Authors:  Dino Samartzis; D Greg Anderson; Francis H Shen
Journal:  Spine (Phila Pa 1976)       Date:  2005-12-01       Impact factor: 3.468

Review 5.  Surgical innovations: impact on the quality of life of the older patient.

Authors:  Thomas R Hornick
Journal:  Clin Geriatr Med       Date:  2006-08       Impact factor: 3.076

Review 6.  Complications of the spine in ankylosing spondylitis with a focus on deformity correction.

Authors:  Matthew L Mundwiler; Khawar Siddique; Jeffrey M Dym; Brian Perri; J Patrick Johnson; Michael H Weisman
Journal:  Neurosurg Focus       Date:  2008       Impact factor: 4.047

Review 7.  Spinal fractures in patients with ankylosing spinal disorders: a systematic review of the literature on treatment, neurological status and complications.

Authors:  L A Westerveld; J J Verlaan; F C Oner
Journal:  Eur Spine J       Date:  2008-09-13       Impact factor: 3.134

8.  Spinal pseudarthrosis in advanced ankylosing spondylitis with sagittal plane deformity: clinical characteristics and outcome analysis.

Authors:  Ki-Tack Kim; Sang-Hun Lee; Kyung-Soo Suk; Jung-Hee Lee; Yang-Jin Im
Journal:  Spine (Phila Pa 1976)       Date:  2007-07-01       Impact factor: 3.468

9.  Evaluation of quality of life using ASQoL questionnaire in patients with ankylosing spondylitis in a Chinese population.

Authors:  L K Zhao; Z T Liao; C H Li; T W Li; J Wu; Q Lin; F Huang; D T Yu; J R Gu
Journal:  Rheumatol Int       Date:  2006-11-14       Impact factor: 3.580

Review 10.  Discovertebral (Andersson) lesions of the spine in ankylosing spondylitis revisited.

Authors:  Johannes L Bron; Mirjam K de Vries; Marieke N Snieders; Irene E van der Horst-Bruinsma; Barend J van Royen
Journal:  Clin Rheumatol       Date:  2009-03-18       Impact factor: 2.980

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  11 in total

1.  Treatment of Andersson lesion-complicating ankylosing spondylitis via transpedicular subtraction and disc resection osteotomy, a retrospective study.

Authors:  Xuesong Zhang; Yao Wang; Bing Wu; Wenhao Hu; Zhifa Zhang; Yan Wang
Journal:  Eur Spine J       Date:  2015-09-07       Impact factor: 3.134

2.  Comments on Fuster et al.: prospective comparison of whole-body (18)F-FDG PET/CT and MRI of the spine in the diagnosis of haematogenous spondylodiscitis.

Authors:  Michael Soussan
Journal:  Eur J Nucl Med Mol Imaging       Date:  2014-10-14       Impact factor: 9.236

3.  Results of in situ fixation of Andersson lesion by posterior approach in 35 cases.

Authors:  B R Dave; M Kulkarni; V Patidar; D Devanand; S Mayi; C Reddy; M Singh; R R Rai; A Krishnan
Journal:  Musculoskelet Surg       Date:  2021-05-26

4.  Andersson lesion in ankylosing spondylitis.

Authors:  Urmila Dhakad; Siddharth K Das
Journal:  BMJ Case Rep       Date:  2013-04-03

Review 5.  An infected Andersson lesion presented with incomplete paraplegia in a patient with ankylosing spondylitis. A unique case report with literature review.

Authors:  Ioannis Papaioannou; Georgia Pantazidou; Thomas Repantis; Andreas Baikousis; Panagiotis Korovessis
Journal:  Spinal Cord Ser Cases       Date:  2022-08-09

Review 6.  Management of Andersson lesions of spine: A systematic review of the existing literature.

Authors:  P Venkata Sudhakar; Pankaj Kandwal; Kaustubh Ahuja Mch; Syed Ifthekar; Samarth Mittal; Bhaskar Sarkar
Journal:  J Clin Orthop Trauma       Date:  2022-04-22

7.  Posterior wedge osteotomy and debridement for Andersson lesion with severe kyphosis in ankylosing spondylitis.

Authors:  Yan Liang; Xiangyu Tang; Yongfei Zhao; Zheng Wang
Journal:  J Orthop Surg Res       Date:  2017-03-31       Impact factor: 2.359

8.  Management of Andersson Lesion in Ankylosing Spondylitis Using the Posterior-Only Approach: A Case Series of 18 Patients.

Authors:  Ismail Shaik; Shekhar Yeshwant Bhojraj; Gautam Prasad; Premik Bhupendra Nagad; Priyank Mangaldas Patel; Aaditya Dattatreya Kashikar; Nishant Kumar
Journal:  Asian Spine J       Date:  2018-10-16

9.  [Debridement and interbody fusion via posterior pedicle lateral approach for ankylosing spondylitis with thoracolumbar Andersson lesion].

Authors:  Keyuan Ding; Jinwen Zhu; Hao Chen; Ye Tian; Dingjun Hao
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2019-12-15

10.  Circumferential Fusion through All-Posterior Approach in Andersson Lesion.

Authors:  Sreekanth Reddy Rajoli; Rishi Mugesh Kanna; Siddharth N Aiyer; Ajoy Prasad Shetty; Shanmuganathan Rajasekaran
Journal:  Asian Spine J       Date:  2017-06-15
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