Polyneuropathies in paediatrics.

Non-acute polyneuropathies (PNPs) encountered in paediatrics are reviewed. Emphasis is placed on three main groups of conditions: the relatively rare but treatable dysimmune PNP (chronic relapsing dysimmune polyneuropathies, CRDP); the more common hereditary motor/sensory neuropathies (HMSN and HSN); and the often missed symptomatic neuropathies of some heredodegenerative and neurometabolic disorders. Diagnostic procedures are discussed. One conclusion drawn is that so far metabolic screening procedures do not give any diagnostic or aetiological information in HMSN or in HSN, nor in heredoataxias or heredoparaplegias. When a specific neurometabolic disease is suspected from the clinical symptomatology, individually structured investigations are necessary.