| Literature DB >> 21557636 |
Iwona Wertel1, Aldona Nowicka, Ewelina Rogala, Jan Kotarski.
Abstract
The development of epithelial ovarian cancer is associated with changes in the peritoneal cavity microenvironment. Tumor cells produce different factors, which impairs differentiation, maturation, and function of antigen-presenting cells. In this review, we focus on selected cell populations in the peritoneal cavity immune system and their potential role in epithelial ovarian cancer immunopathogenesis. We devote most attention to dendritic cells because they are considered to be superior in their antigen-presenting ability, compared with both macrophages and B lymphocytes. We also present a brief characterization of tumor-infiltraiting cells in epithelial ovarian cancer patients.Entities:
Mesh:
Year: 2011 PMID: 21557636 DOI: 10.3109/08830185.2011.569902
Source DB: PubMed Journal: Int Rev Immunol ISSN: 0883-0185 Impact factor: 5.311