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Literature DB >> 215548

Comparison of various macrophage-inhibitory agents on vaginal and systemic herpes simplex virus type 2 infections.

Abstract

Pretreatment of mice intraperitoneally with silica, trypan blue, or dextran sulfate to inhibit macrophage function markedly increased the lethality of a systemic intravenous infection with herpes simplex virus type 2, but did not affect the lethality or local virus growth after vaginal infection of mice with herpes simplex virus type 2. Agents which inhibit macrophage function by different mechanisms decreased host resistance to herpes simplex virus type 2, but the effects of macrophage-inhibitory agents may vary according to the route of virus infection.

Entities: Chemical Disease Species

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Year: 1978 PMID： 215548 PMCID： PMC422201 DOI： 10.1128/iai.22.2.623-626.1978

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

28 in total

1. Host defense mechanisms against infectious bovine rhinotracheitis virus. II. Inhibition of viral plaque formation by immune peripheral blood lymphocytes.

Authors: B T Rouse; L A Babiuk
Journal: Cell Immunol Date: 1975-05 Impact factor: 4.868

2. Effect of silica on virus infections in mice and mouse tissue culture.

Authors: H duBuy
Journal: Infect Immun Date: 1975-05 Impact factor: 3.441

3. Immunomodulator-induced resistance against herpes simplex virus.

Authors: P S Morahan; E R Kern; L A Glasgow
Journal: Proc Soc Exp Biol Med Date: 1977-04

4. Specific lethality of silica for human peripheral blood mononuclear phagocytes, in vitro.

Authors: E J O'Rourke; S B Halstead; A C Allison; T A Platts-Mills
Journal: J Immunol Methods Date: 1978 Impact factor: 2.303

5. Abrogation of tumor rejection by trypan blue.

Authors: J W Kreider; G L Bartlett; E DeFreitas
Journal: Cancer Res Date: 1978-04 Impact factor: 12.701

6. Promotion of tumor growth in vivo by antimacrophage agents.

Authors: R Keller
Journal: J Natl Cancer Inst Date: 1976-12 Impact factor: 13.506

7. Effects of trypan blue treatment on the immune responses of mice.

Authors: M L Kripke; K C Norbury; E Gruys; J B Hibbs
Journal: Infect Immun Date: 1977-07 Impact factor: 3.441

8. Hepatic clearance of Salmonella typhimurium in silica-treated mice.

Authors: R L Friedman; R J Moon
Journal: Infect Immun Date: 1977-06 Impact factor: 3.441

9. Effects of Dextran Sulfate 500 on Cell-Mediated Resistance to Infection with Listeria monocytogenes in Mice.

Authors: H Hahn
Journal: Infect Immun Date: 1974-11 Impact factor: 3.441

10. Immunological mechanisms in metastatic spread and the antimetastatic effects of C. parvum.

Authors: P D Jones; J E Castro
Journal: Br J Cancer Date: 1977-05 Impact factor: 7.640

8 in total

1. Permissiveness of rabbit monocytes and macrophages for herpes simplex virus type 1.

Authors: S Plaeger-Marshall; L A Wilson; J W Smith
Journal: Infect Immun Date: 1982-01 Impact factor: 3.441

2. Lymphocyte-derived chemotactic factor synthesis in initial genital herpesvirus infection: correlation with lymphocyte transformation.

Authors: M C Rattray; G M Peterman; L C Altman; L Corey; K K Holmes
Journal: Infect Immun Date: 1980-10 Impact factor: 3.441

8. Antimicrobial activity of various immunomodulators: independence from normal levels of circulating monocytes and natural killer cells.

Authors: P S Morahan; W L Dempsey; A Volkman; J Connor
Journal: Infect Immun Date: 1986-01 Impact factor: 3.441