BACKGROUND AND OBJECTIVE: To assess the prevalence of peripheral fundus autofluorescence (FAF) abnormalities in chronic Vogt-Koyanagi-Harada disease (VKH). PATIENTS AND METHODS: A retrospective review of cases at the Doheny Eye Institute between December 2009 and April 2010. Patients with chronic VKH who had ultra-wide-field FAF and pseudo-color imaging performed were included. All images were reviewed independently by two reading center certified retina specialists. RESULTS: Twenty eyes of 10 patients were included in this analysis. Fourteen eyes of 7 patients (70%) showed peripheral changes on FAF images outside the posterior pole. Three different patterns were observed: multifocal hypofluorescent spots (n = 11 eyes), hyperfluorescent spots (n = 8 eyes), and a unique lattice-like pattern in both eyes of one patient. There were noticeable disparities between FAF and color images. CONCLUSION: Peripheral FAF abnormalities are frequent in chronic VKH and are readily revealed by wide-field FAF imaging and manifesting with distinct patterns. Further investigation in prospective studies is warranted. Copyright 2011, SLACK Incorporated.
BACKGROUND AND OBJECTIVE: To assess the prevalence of peripheral fundus autofluorescence (FAF) abnormalities in chronic Vogt-Koyanagi-Harada disease (VKH). PATIENTS AND METHODS: A retrospective review of cases at the Doheny Eye Institute between December 2009 and April 2010. Patients with chronic VKH who had ultra-wide-field FAF and pseudo-color imaging performed were included. All images were reviewed independently by two reading center certified retina specialists. RESULTS: Twenty eyes of 10 patients were included in this analysis. Fourteen eyes of 7 patients (70%) showed peripheral changes on FAF images outside the posterior pole. Three different patterns were observed: multifocal hypofluorescent spots (n = 11 eyes), hyperfluorescent spots (n = 8 eyes), and a unique lattice-like pattern in both eyes of one patient. There were noticeable disparities between FAF and color images. CONCLUSION: Peripheral FAF abnormalities are frequent in chronic VKH and are readily revealed by wide-field FAF imaging and manifesting with distinct patterns. Further investigation in prospective studies is warranted. Copyright 2011, SLACK Incorporated.
Authors: Tobias Duncker; Jonathan P Greenberg; Janet R Sparrow; R Theodore Smith; Harry A Quigley; François C Delori Journal: Invest Ophthalmol Vis Sci Date: 2012-09-28 Impact factor: 4.799
Authors: Felipe T da Silva; Carlos E Hirata; Viviane M Sakata; Edilberto Olivalves; Rony Preti; Sergio L G Pimentel; Andre Gomes; Walter Y Takahashi; Rogerio A Costa; Joyce H Yamamoto Journal: BMC Ophthalmol Date: 2012-08-13 Impact factor: 2.209