INTRODUCTION: Exact pathological staging of bladder cancer is crucial for determination of further treatment. One limiting factor is the surgical 'incise and scatter' technique that might contribute to tumour recurrence. En bloc resection techniques are en emerging issue. We present initial results with Thulium:YAG (Tm:YAG) en bloc resection of bladder tumours for treatment and accurate staging of solitary transitional cell carcinoma of the bladder. MATERIALS AND METHODS: From June through October 2010, six patients were treated by TmLRBT (Thulium laser resection of bladder tumour). Inclusion criteria were solitary lesions, treatment naive patients and tumour localisation of the lower bladder wall and trigonum. En bloc resection was applied on all of the tumours. Two cold-cut biopsies from the tumour base were extracted. On five of the six patients, a re-resection was performed after 6 weeks. RESULTS: Pathological evaluation revealed 1 patient with pTa G1, 2 patients with pTa G2 and 3 patients with pT1 G3. All of the resected specimens provided detrusor muscle, and all biopsies were positive for muscle cells. No intra-, peri- or post-operative complications were observed. Bladder irrigation was mandatory in only 50% of the patients. All patients were negative for residual TCC in re-resection 6 weeks after initial treatment. CONCLUSION: TmLRBT has been proven safe and effective for both, treatment and pathological staging of primary TCC of the bladder. Tm:YAG en bloc resection therefore could be an appropriate tool for accurate staging with possibly lower scattering potential for the assessment and treatment of patients with TCC.
INTRODUCTION: Exact pathological staging of bladder cancer is crucial for determination of further treatment. One limiting factor is the surgical 'incise and scatter' technique that might contribute to tumour recurrence. En bloc resection techniques are en emerging issue. We present initial results with Thulium:YAG (Tm:YAG) en bloc resection of bladder tumours for treatment and accurate staging of solitary transitional cell carcinoma of the bladder. MATERIALS AND METHODS: From June through October 2010, six patients were treated by TmLRBT (Thulium laser resection of bladder tumour). Inclusion criteria were solitary lesions, treatment naive patients and tumour localisation of the lower bladder wall and trigonum. En bloc resection was applied on all of the tumours. Two cold-cut biopsies from the tumour base were extracted. On five of the six patients, a re-resection was performed after 6 weeks. RESULTS: Pathological evaluation revealed 1 patient with pTa G1, 2 patients with pTa G2 and 3 patients with pT1 G3. All of the resected specimens provided detrusor muscle, and all biopsies were positive for muscle cells. No intra-, peri- or post-operative complications were observed. Bladder irrigation was mandatory in only 50% of the patients. All patients were negative for residual TCC in re-resection 6 weeks after initial treatment. CONCLUSION: TmLRBT has been proven safe and effective for both, treatment and pathological staging of primary TCC of the bladder. Tm:YAG en bloc resection therefore could be an appropriate tool for accurate staging with possibly lower scattering potential for the assessment and treatment of patients with TCC.
Authors: Sergio Coda; Paolo Trentino; Fabio Antonellis; Barbara Porowska; Francesco Gossetti; Franco Ruberto; Francesco Pugliese; Giulia D'Amati; Paolo Negro; Takuji Gotoda Journal: Gastric Cancer Date: 2010-12-03 Impact factor: 7.370
Authors: Song Xishuang; Yang Deyong; Che Xiangyu; Jiang Tao; Li Quanlin; Guan Hongwei; Yin Jibin; Wu Dongjun; He Zhongzhou; Wang Jianbo; Wang Lina; Ye Lin Journal: J Endourol Date: 2010-01 Impact factor: 2.942
Authors: M W Kramer; M Wolters; I F Abdelkawi; A S Merseburger; U Nagele; A Gross; T Bach; M A Kuczyk; T R W Herrmann Journal: Urologe A Date: 2012-06 Impact factor: 0.639
Authors: Mario W Kramer; Thorsten Bach; Mathias Wolters; Florian Imkamp; Andreas J Gross; Markus A Kuczyk; Axel S Merseburger; Thomas R W Herrmann Journal: World J Urol Date: 2011-05-05 Impact factor: 4.226
Authors: Mario W Kramer; Jens J Rassweiler; Jan Klein; Alexey Martov; Nikolay Baykov; Lukas Lusuardi; Günter Janetschek; Rodolfo Hurle; Mathias Wolters; Mahmoud Abbas; Christoph A von Klot; Armin Leitenberger; Markus Riedl; Udo Nagele; Axel S Merseburger; Markus A Kuczyk; Marko Babjuk; Thomas R W Herrmann Journal: World J Urol Date: 2015-04-25 Impact factor: 4.226
Authors: Mario W Kramer; Mathias Wolters; Hannes Cash; Stephan Jutzi; Florian Imkamp; Markus A Kuczyk; Axel S Merseburger; Thomas R W Herrmann Journal: World J Urol Date: 2014-06-17 Impact factor: 4.226