Literature DB >> 21553275

Multicystic dysplastic kidney: our experience in non-surgical management.

Aurelie Chiappinelli1, Antonio Savanelli, Alessandra Farina, Alessandro Settimi.   

Abstract

INTRODUCTION: Although multicystic dysplastic kidney (MDK) is a common renal anomaly, the management of this condition remains controversial. The purpose of this study was to focus on its regression by ultrasound (US) scan for MDK managed conservatively.
MATERIALS AND METHODS: Between 1990 and 2010, 50 children with MDK were retrospectively studied. All patients were submitted to radioisotope scan to confirm the diagnosis, and a micturating cystogram to exclude other uropathies.
RESULTS: Of the 50 patients, 19 underwent nephrectomy, and the other 31 were conservatively managed with clinical and US scan follow-up. The mean follow-up time (range 6 months to 11 years) in the non-operated group was 6.2 years. Of the 31 children with nonsurgical management, 17 (54.8%) showed total involution on US scan, 7 (22.6%) showed a partial regression, and 7 (22.6%) were unchanged at the time of this study. The mean time to complete disappearance on US scan was 2.5 years (1-4 years). No children developed hypertension or tumors. DISCUSSION: The natural history of MDK is usually benign, but patients must have long-term follow-up with US scan. In addition, many studies confirmed that the disappearance of it on a US scan does not mean a total involution of the affected kidney. We recommend a strict follow-up even when US scan shows an undetectable kidney.

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Year:  2011        PMID: 21553275     DOI: 10.1007/s00383-011-2910-8

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  19 in total

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Journal:  Pediatrics       Date:  2004-08       Impact factor: 7.124

2.  Unilateral multicystic dysplastic kidney: long term outcomes.

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Review 3.  Risk of Wilms' tumour with multicystic kidney disease: a systematic review.

Authors:  H Narchi
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4.  Unilateral multicystic dysplastic kidney: the case for nephrectomy.

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5.  Multicystic renal dysplasia detected by prenatal ultrasonography. Natural history and results of conservative management.

Authors:  A M Rickwood; P A Anderson; M P Williams
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Review 6.  Risk of hypertension with multicystic kidney disease: a systematic review.

Authors:  H Narchi
Journal:  Arch Dis Child       Date:  2005-05-04       Impact factor: 3.791

7.  Natural history of multicystic kidney conservatively managed: a prospective study.

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8.  Antenatal diagnostic aspects of unilateral multicystic kidney dysplasia--sensitivity, specificity, predictive values, differential diagnoses, associated malformations and consequences.

Authors:  Felicitas Eckoldt; R Woderich; R D Smith; K-S Heling
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Review 9.  Management and etiology of the unilateral multicystic dysplastic kidney: a review.

Authors:  David S Hains; Carlton M Bates; Susan Ingraham; Andrew L Schwaderer
Journal:  Pediatr Nephrol       Date:  2008-05-15       Impact factor: 3.714

10.  Does the multicystic dysplastic kidney really involute? The role of the retroperitoneoscopic approach.

Authors:  R Luque-Mialdea; R Martín-Crespo; J Cebrian; L Moreno; C Carrero; A Fernández
Journal:  J Pediatr Urol       Date:  2006-03-30       Impact factor: 1.830

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  2 in total

1.  Multicystic dysplastic kidney (MCDK) in the neonate: The role of the urologist.

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Journal:  Can Urol Assoc J       Date:  2016 Jan-Feb       Impact factor: 1.862

2.  Applicability of Laparoscopic Nephrectomy in the Treatment of Multicystic Dysplastic Kidney: Sorting Out Surgical Indication.

Authors:  Carlos Augusto F Molina; Jose Bessa Junior; Andrey G Estevanato; Gustavo S Viana; Inalda Facincani; Jose Murillo Bastos Netto; Silvio Tucci Junior
Journal:  Cureus       Date:  2018-01-01
  2 in total

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