Baris Afsar1, Rengin Elsurer. 1. Department of Nephrology, Zonguldak Atatürk State Hospital, Mesrutiyet Mah, Mustafa türkcelik Sok, Büsra Sitesi C Blok, 67100 Zonguldak, Turkey. afsarbrs@yahoo.com
Abstract
OBJECTIVES: Presence of diabetes mellitus has been shown to be related with the occurrence of primary arteriovenous fistula (AVF) failure in some but not in all studies. In the current study, we examined whether glycemic control as evaluated by HbA1c is independently related with primary AVF failure. METHODS: We recorded sociodemographic, clinical, and laboratory parameters of the patients from medical records and hospital charts prior to AVF surgery. Primary AVF failure was described as a complication of the AVF before the first successful cannulation for HD treatment. RESULTS: Our study comprised of 160 non-diabetic (Group1) and 73 diabetic patients. Among diabetic patients, 37 had HbA1c values <7% (Group 2) and 36 patients had HbA1c values ≥7% (Group 3). In total, 74 (31.8%) patients had a history of primary AVF failure. The percentages of primary AVF failure were 27.5, 29.7, and 52.8% in Group 1, Group 2, and Group 3, respectively (P: 0.013). The percentage of patients with primary AVF failure was significantly lower in Group 1 and Group 2 than in Group 3 (P:0.003 and P:0.045, respectively). There was no difference with respect to primary AVF failure between Group 1 and Group 2 patients. CONCLUSIONS: We suggest that poor glycemic control as assessed by HbA1c may be an important factor for the development of primary AVF failure among diabetic subjects. It is possible that differences with respect to AVF failure between diabetic and non-diabetic patients may be partly attributed to glycemic control.
OBJECTIVES: Presence of diabetes mellitus has been shown to be related with the occurrence of primary arteriovenous fistula (AVF) failure in some but not in all studies. In the current study, we examined whether glycemic control as evaluated by HbA1c is independently related with primary AVF failure. METHODS: We recorded sociodemographic, clinical, and laboratory parameters of the patients from medical records and hospital charts prior to AVF surgery. Primary AVF failure was described as a complication of the AVF before the first successful cannulation for HD treatment. RESULTS: Our study comprised of 160 non-diabetic (Group1) and 73 diabeticpatients. Among diabeticpatients, 37 had HbA1c values <7% (Group 2) and 36 patients had HbA1c values ≥7% (Group 3). In total, 74 (31.8%) patients had a history of primary AVF failure. The percentages of primary AVF failure were 27.5, 29.7, and 52.8% in Group 1, Group 2, and Group 3, respectively (P: 0.013). The percentage of patients with primary AVF failure was significantly lower in Group 1 and Group 2 than in Group 3 (P:0.003 and P:0.045, respectively). There was no difference with respect to primary AVF failure between Group 1 and Group 2 patients. CONCLUSIONS: We suggest that poor glycemic control as assessed by HbA1c may be an important factor for the development of primary AVF failure among diabetic subjects. It is possible that differences with respect to AVF failure between diabetic and non-diabeticpatients may be partly attributed to glycemic control.
Authors: Elizabeth Selvin; Spyridon Marinopoulos; Gail Berkenblit; Tejal Rami; Frederick L Brancati; Neil R Powe; Sherita Hill Golden Journal: Ann Intern Med Date: 2004-09-21 Impact factor: 25.391
Authors: Takeshi Hasegawa; Stacey J Elder; Jennifer L Bragg-Gresham; Ronald L Pisoni; Shin Yamazaki; Tadao Akizawa; Michel Jadoul; Rayner C Hugh; Friedrich K Port; Shunichi Fukuhara Journal: Clin J Am Soc Nephrol Date: 2008-07-02 Impact factor: 8.237
Authors: Yan Yan; Dan Ye; Liu Yang; Wen Ye; Dandan Zhan; Li Zhang; Jun Xiao; Yan Zeng; Qinkai Chen Journal: Ren Fail Date: 2018-11 Impact factor: 2.606