| Literature DB >> 21552424 |
Yongsung Joo1, G Casella, J Hobert.
Abstract
Cluster analysis has been widely used to explore thousands of gene expressions from microarray analysis and identify a small number of similar genes (objects) for further detailed biological investigation. However, most clustering algorithms tend to identify loose clusters with too many genes. In this paper, we propose a Bayesian tight clustering method for time course gene expression data, which selects a small number of closely-related genes and constructs tight clusters only with these closely-related genes.Entities:
Year: 2010 PMID: 21552424 PMCID: PMC3087980 DOI: 10.1007/s00180-009-0159-7
Source DB: PubMed Journal: Comput Stat ISSN: 0943-4062 Impact factor: 1.000