Literature DB >> 2155139

The relationship of plasminogen activators and oncogenes to tumour invasion.

J S Gelister1, P B Boulos, P J Gaffney, M Mahmoud, M R Lewin.   

Abstract

Accruing evidence suggests an association between increased activity of plasminogen activators and transformed cells, and urokinase activity with tumour aggressiveness. The PIP2 pathway seems to provide a link between oncogene-associated transformation, cellular proliferation, plasminogen-activator expression and tumour invasion and metastasis.

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Year:  1990        PMID: 2155139

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  1 in total

1.  Plasminogen activators and inhibitor type 1 in neoplastic colonic tissue from patients with familial adenomatous polyposis.

Authors:  C F Sier; H J Vloedgraven; G Griffioen; S Ganesh; F M Nagengast; C B Lamers; H W Verspaget
Journal:  Br J Cancer       Date:  1995-02       Impact factor: 7.640

  1 in total

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