OBJECTIVE: To determine to what degree annual reports from ages 14 to 19 years of menstrual cycles ≥42 days would be associated with increased body mass index (BMI), waist circumference, glucose, insulin, and homeostasis model assessment insulin resistance (HOMA-IR) at ages 14-25 years. DESIGN: Prospective 11-year follow-up from ages 14 to 25 years. SETTING: Urban-suburban schools, post-high school. PATIENT(S): A total of 370 schoolgirls. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): BMI, waist, insulin, glucose, HOMA-IR. RESULT(S): From ages 14 to 19 years, 269 girls had 0/6 annual reports of menstrual cycles ≥42 days, 74 had 1, 19 had 2, and 8 had ≥3. Among these four categories, girls with ≥3 annual reports had highest free T and DHEAS at age 14, highest BMI and waist at ages 14, 19, and 25, highest insulin at age 25, and highest glucose and HOMA-IR at age 24 years. The number of annual reports of menstrual cycles ≥42 days was positively related to change in BMI and waist and inversely with change in high-density lipoprotein cholesterol from ages 14 to 25 years. CONCLUSION(S): Three or more annual reports of menstrual cycles ≥42 days during ages 14-19 are associated with high BMI, waist circumference, insulin, glucose, and HOMA-IR at ages 14-25 years.
OBJECTIVE: To determine to what degree annual reports from ages 14 to 19 years of menstrual cycles ≥42 days would be associated with increased body mass index (BMI), waist circumference, glucose, insulin, and homeostasis model assessment insulin resistance (HOMA-IR) at ages 14-25 years. DESIGN: Prospective 11-year follow-up from ages 14 to 25 years. SETTING: Urban-suburban schools, post-high school. PATIENT(S): A total of 370 schoolgirls. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): BMI, waist, insulin, glucose, HOMA-IR. RESULT(S): From ages 14 to 19 years, 269 girls had 0/6 annual reports of menstrual cycles ≥42 days, 74 had 1, 19 had 2, and 8 had ≥3. Among these four categories, girls with ≥3 annual reports had highest free T and DHEAS at age 14, highest BMI and waist at ages 14, 19, and 25, highest insulin at age 25, and highest glucose and HOMA-IR at age 24 years. The number of annual reports of menstrual cycles ≥42 days was positively related to change in BMI and waist and inversely with change in high-density lipoprotein cholesterol from ages 14 to 25 years. CONCLUSION(S): Three or more annual reports of menstrual cycles ≥42 days during ages 14-19 are associated with high BMI, waist circumference, insulin, glucose, and HOMA-IR at ages 14-25 years.
Authors: S Y Kimm; B A Barton; E Obarzanek; R P McMahon; Z I Sabry; M A Waclawiw; G B Schreiber; J A Morrison; S Similo; S R Daniels Journal: Pediatrics Date: 2001-03 Impact factor: 7.124
Authors: M H van Hooff; F J Voorhorst; M B Kaptein; R A Hirasing; C Koppenaal; J Schoemaker Journal: J Clin Endocrinol Metab Date: 2000-04 Impact factor: 5.958
Authors: Kate A Marsh; Katharine S Steinbeck; Fiona S Atkinson; Peter Petocz; Jennie C Brand-Miller Journal: Am J Clin Nutr Date: 2010-05-19 Impact factor: 7.045
Authors: F M Biro; R P McMahon; R Striegel-Moore; P B Crawford; E Obarzanek; J A Morrison; B A Barton; F Falkner Journal: J Pediatr Date: 2001-05 Impact factor: 4.406
Authors: John A Morrison; Charles J Glueck; Muhammad Umar; Stephen Daniels; Lawrence M Dolan; Ping Wang Journal: Metabolism Date: 2010-01-22 Impact factor: 8.694