Literature DB >> 21549970

Black bone disease of the foot. Minocycline related pigmentation.

S D Middleton1, R E Anakwe, J C McKinley.   

Abstract

Black bone disease is a rare manifestation of long term treatment with tetracyclines. We report the case of a patient who underwent surgery for bilateral hallux valgus and was found to have black discolouration of both first rays. This was subsequently related to previous long term Minocycline use. The unique features of this case relate to the location of the discolouration and the normal physical properties of the bone and soft tissues at surgery despite heavy pigmentation. Healing is now complete and follow-up at two years confirmed excellent clinical and radiological outcomes.
Copyright © 2011 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21549970     DOI: 10.1016/j.fas.2011.01.011

Source DB:  PubMed          Journal:  Foot Ankle Surg        ISSN: 1268-7731            Impact factor:   2.705


  3 in total

Review 1.  Tetracyclines and bone: Unclear actions with potentially lasting effects.

Authors:  Amy J Warner; Jessica D Hathaway-Schrader; Rena Lubker; Christopher Davies; Chad M Novince
Journal:  Bone       Date:  2022-03-03       Impact factor: 4.626

2.  Black bone disease in a healing fracture.

Authors:  Desmond Thiam; Tse Yean Teo; Rishi Malhotra; Kong Bing Tan; Yu Han Chee
Journal:  BMJ Case Rep       Date:  2016-01-28

3.  Black Colouration of the Knee Articular Cartilage after Spontaneously Recurrent Haemarthrosis.

Authors:  Kazu Matsumoto; Daichi Ishimaru; Hiroyasu Ogawa; Haruhiko Akiyama
Journal:  Case Rep Orthop       Date:  2016-05-12
  3 in total

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