Literature DB >> 21549552

[Prevalence of latent tuberculosis infection among health care workers from the emergency department of Meaux hospital using an interferon gamma release assay].

Frédéric Faibis1, Dominique Castelain, Marie-Claude Moreau, Jocelyne Tellier, Ahmed Dekimeche, Hélène Ittah-Desmeulles, Alain Fiacre, Marie-Claude Demachy.   

Abstract

OBJECTIVE: To determine the prevalence of the latent tuberculosis infection (LTBI) among health care workers (HCW) of the emergency ward of Meaux hospital, by comparing it with two witnesses units: the orthopaedic surgery ward (referral service to low risk) and the respiratory ward (referral service to high risk).
METHODS: From July to December 2008, on a voluntary basis, anonymised blood samples of any HCW of the three departments were carried out by the occupational health service. Determination of interferon gamma was released by the test "QuantiFERON-TB Gold" (QFT).
RESULTS: Of the 137 eligible subject sampled, 16 had a positive QFT test: nine in the emergency ward, six in the respiratory ward and one in the orthopaedic surgery ward. The proportion of HCW with a positive QFT test was not significantly different between the three wards. DISCUSSION: This study shows that HCWs of the emergency ward of the Meaux hospital are not working in a department where the risk of LTBI is high.
CONCLUSION: Our study shows that, in a territory of health where the incidence of the tuberculosis disease is superior to the national average, the emergency department of Meaux hospital does not belong to an area at high risk of LTBI. It underlines the interest of QFT test for the screening of LTBI among vaccinated persons.
Copyright © 2011 Elsevier Masson SAS. All rights reserved.

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Year:  2011        PMID: 21549552     DOI: 10.1016/j.lpm.2011.03.014

Source DB:  PubMed          Journal:  Presse Med        ISSN: 0755-4982            Impact factor:   1.228


  3 in total

1.  The effect of introducing IGRA to screen French healthcare workers for tuberculosis and potential conclusions for the work organisation.

Authors:  Adrien Moucaut; Albert Nienhaus; Benedicte Courtois; Virginie Nael; Claire Longuenesse; Bruno Ripault; Pierre Rucay; Stéphanie Moisan; Yves Roquelaure; Dominique Tripodi
Journal:  J Occup Med Toxicol       Date:  2013-05-07       Impact factor: 2.646

2.  Tuberculosis screening at the Sainte-Anne Hospital in Paris - results of first and second IGRA.

Authors:  Albert Nienhaus; Paul-Kenneth Gariepy; Catherine Trouve; Christiane Lhaumet; Jean Toureau; Claudia Peters
Journal:  J Occup Med Toxicol       Date:  2014-07-08       Impact factor: 2.646

3.  Risk of Occupational Latent Tuberculosis Infection among Health Personnel Measured by Interferon-Gamma Release Assays in Low Incidence Countries-A Systematic Review and Meta-Analysis.

Authors:  Claudia Peters; Agnessa Kozak; Albert Nienhaus; Anja Schablon
Journal:  Int J Environ Res Public Health       Date:  2020-01-16       Impact factor: 3.390

  3 in total

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