Literature DB >> 21547147

The epidemic of nonmelanoma skin cancer and the widespread use of statins: Is there a connection?

Luca Mascitelli1, Francesca Pezzetta, Mark R Goldstein.   

Abstract

We hypothesize that some of the mechanisms involved in the "epidemic" of nonmelanoma skin cancer might also be due to widespread use of cholesterol lowering statin drugs.

Entities:  

Keywords:  cholesterol; epidemiology; immunomodulation; nonmelanoma skincancer; risk factors; statins; transplantation

Year:  2010        PMID： 21547147      PMCID： PMC3084964          DOI： 10.4161/derm.2.1.12128

Source DB:  PubMed          Journal:  Dermatoendocrinol        ISSN： 1938-1972


  19 in total

Review 1.  Skin cancers after organ transplantation.

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Review 2.  Immunosenescence of ageing.

Authors:  A L Gruver; L L Hudson; G D Sempowski
Journal:  J Pathol       Date:  2007-01       Impact factor: 7.996

3.  Statins, Tregs and cancer.

Authors:  Mark R Goldstein; Luca Mascitelli; Francesca Pezzetta
Journal:  Atherosclerosis       Date:  2007-10-30       Impact factor: 5.162

4.  The editor's roundtable: the JUPITER trial--initial results and clinical implications.

Authors:  Paul M Ridker; Vincent E Friedewald; Michael H Davidson; James T Willerson; William C Roberts
Journal:  Am J Cardiol       Date:  2009-05-15       Impact factor: 2.778

5.  The janus face of immunosuppression - de novo malignancy after renal transplantation: the experience of the Transplantation Center Munich.

Authors:  C D Wimmer; M Rentsch; A Crispin; W D Illner; H Arbogast; C Graeb; K-W Jauch; M Guba
Journal:  Kidney Int       Date:  2007-02-28       Impact factor: 10.612

Review 6.  Tregs and rethinking cancer immunotherapy.

Authors:  Tyler J Curiel
Journal:  J Clin Invest       Date:  2007-05       Impact factor: 14.808

7.  Cancer after kidney transplantation in the United States.

Authors:  Bertram L Kasiske; Jon J Snyder; David T Gilbertson; Changchun Wang
Journal:  Am J Transplant       Date:  2004-06       Impact factor: 8.086

Review 8.  Squamous cell carcinoma in solid-organ transplantation.

Authors:  Jashin J Wu; Ida F Orengo
Journal:  Dermatol Online J       Date:  2002-10

9.  Prevalence of Foxp3 positive T regulatory cells is increased during progression of cutaneous squamous tumors.

Authors:  Tae Jung Jang
Journal:  Yonsei Med J       Date:  2008-12-31       Impact factor: 2.759

10.  MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial.

Authors: 
Journal:  Lancet       Date:  2002-07-06       Impact factor: 79.321
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  5 in total

1.  Dermato-Endocrinology: A continuously growing field with many fascinating facets!

Authors:  Jörg Reichrath
Journal:  Dermatoendocrinol       Date:  2010-01

2.  Statin use and risk of skin cancer.

Authors:  Brian M Lin; Wen-Qing Li; Eunyoung Cho; Gary C Curhan; Abrar A Qureshi
Journal:  J Am Acad Dermatol       Date:  2017-12-05       Impact factor: 11.527

3.  The statin-iron nexus: anti-inflammatory intervention for arterial disease prevention.

Authors:  Leo R Zacharski; Ralph G DePalma; Galina Shamayeva; Bruce K Chow
Journal:  Am J Public Health       Date:  2013-02-14       Impact factor: 9.308

4.  Impact of cholesterol on disease progression.

Authors:  Chun-Jung Lin; Cheng-Kuo Lai; Min-Chuan Kao; Lii-Tzu Wu; U-Ging Lo; Li-Chiung Lin; Yu-An Chen; Ho Lin; Jer-Tsong Hsieh; Chih-Ho Lai; Chia-Der Lin
Journal:  Biomedicine (Taipei)       Date:  2015-06-01

5.  Relation of statin use with non-melanoma skin cancer: prospective results from the Women's Health Initiative.

Authors:  Ange Wang; Marcia L Stefanick; Kristopher Kapphahn; Haley Hedlin; Manisha Desai; Jo Ann E Manson; Howard Strickler; Lisa Martin; Jean Wactawski-Wende; Michael Simon; Jean Y Tang
Journal:  Br J Cancer       Date:  2016-01-07       Impact factor: 7.640
  5 in total

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