| Literature DB >> 21547117 |
Francesco Bifari1, Veronica Lisi, Elda Mimiola, Annalisa Pasini, Mauro Krampera.
Abstract
SUMMARY: Mesenchymal stem cells (MSCs) and their stromal progeny may be considered powerful regulatory cells, a sort of dendritic cell counterpart, which influence all the main immune effectors and functional roles in vivo, as well as potential applications in the treatment of a number of human immunological diseases. By choosing MSC tissue origin, cell dose, administration route, and treatment schedule, all the potential side effects related to MSC use, including tumor growth enhancement, have to be well considered to maximize the benefits of MSC-depen-dent immune regulation without significant risks for the patients.Entities:
Year: 2008 PMID: 21547117 PMCID: PMC3083287 DOI: 10.1159/000128968
Source DB: PubMed Journal: Transfus Med Hemother ISSN: 1660-3796 Impact factor: 3.747