| Literature DB >> 21546163 |
Renaud Mazeron1, Bethany Anderson, Stéphane Supiot, François Paris, Eric Deutsch.
Abstract
Angiogenesis has been a central theme of oncologic research for several years. Recently, improved understanding of its mechanisms has led to the development of several antiangiogenic agents. Some have demonstrated their effectiveness in large randomized studies; however, no antiangiogenic agent has yet been approved for treatment in combination with radiotherapy. Numerous preclinical studies and a few small clinical trials have recently reported encouraging results. The objective of this article is to review the concept of targeted antiangiogenic agents and the early clinical results of their use in combination with radiation therapy.Mesh：
Substances：
Year: 2011 PMID： 21546163 DOI： 10.1016/j.ctrv.2011.03.004
Source DB: PubMed Journal: Cancer Treat Rev ISSN： 0305-7372 Impact factor: 12.111