Literature DB >> 215445

Imbalance in the activities of alkaline phosphatase and Na+-K+-ATPase in the brain of experimentally induced phenylketonuric squirrels (Funambulus palmarum).

D K Bhatt.   

Abstract

Phenylketonuric squirrels have shown marked inhibition of alkaline phosphatase in the olfactory lobes and cerebral hemispheres, whereas the Na+-K+-ATPase remained less altered. In the pathogenesis of phenylketonuria inhibition of alkaline phosphatase at the level of "Blood-Brain Barrier" (BBB), leads transport system to impaired functioning.

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Year:  1978        PMID： 215445     DOI： 10.1007/bf02034665

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  Brain uptake and protein incorporation of amino acids studied in rats subjected to prolonged hyperphenylalaninaemia.

Authors:  K N Antonas; W F Coulson
Journal:  J Neurochem       Date:  1975-09       Impact factor: 5.372

2.  Effect of unilateral visual deprivation and visual stimulation on the activities of alkaline phosphatase, acid phosphatase, Na-+ --K-+ activated Mg-2-+ catalysed adenosine triphosphatase and on the content of sodium and potassium ions of the optic lobe of adult pigeon.

Authors:  T Chakrabarti; H F Daginawala
Journal:  J Neurochem       Date:  1975-05       Impact factor: 5.372

3.  Studies on aromatic amino acid uptake by rat brain in vivo. Uptake of phenylalanine and of tryptophan; inhibition and stereoselectivity in the uptake of tyrosine by brain and muscle.

Authors:  G GUROFF; S UDENFRIEND
Journal:  J Biol Chem       Date:  1962-03       Impact factor: 5.157

4.  Alkaline phosphomonoesterase and blood brain permeability.

Authors:  T SAMORAJSKI; J McCLOUD
Journal:  Lab Invest       Date:  1961 May-Jun       Impact factor: 5.662

5.  Uptake of tyrosine by rat brain in vivo.

Authors:  M A CHIRIGOS; P GREENGARD; S UDENFRIEND
Journal:  J Biol Chem       Date:  1960-07       Impact factor: 5.157

6.  [Active storage of tryptophan in the isolated rat cerebral cortex].

Authors:  E Barbosa; P Joanny; J Corriol
Journal:  C R Seances Soc Biol Fil       Date:  1970-09-25

7.  Histochemical mapping of alkaline phosphatase in the cranial, intrinsic & reticular nuclei & fiber tracts of medulla oblongata & pons of squirrel Funambulus palmarum.

Authors:  D K Bhatt
Journal:  Indian J Exp Biol       Date:  1977-09       Impact factor: 0.818

8.  Electron microscopic observations of the central nervous system.

Authors:  S A LUSE
Journal:  J Biophys Biochem Cytol       Date:  1956-09-25
  8 in total

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