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Literature DB >> 21544137

Biochemistry: life imitates art.

Wendy L Kelly¹.

Abstract

Mesh：

Substances：

Year: 2011 PMID： 21544137 DOI： 10.1038/473035a

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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11 in total

1. Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.

Authors: C Waldron; P Matsushima; P R Rosteck; M C Broughton; J Turner; K Madduri; K P Crawford; D J Merlo; R H Baltz
Journal: Chem Biol Date: 2001-05

2. Total synthesis of (-)-spinosyn A.

Authors: Dustin J Mergott; Scott A Frank; William R Roush
Journal: Proc Natl Acad Sci U S A Date: 2004-06-01 Impact factor: 11.205

3. Macrophomate synthase: QM/MM simulations address the Diels-Alder versus Michael-Aldol reaction mechanism.

Authors: Cristiano Ruch Werneck Guimarães; Marina Udier-Blagović; William L Jorgensen
Journal: J Am Chem Soc Date: 2005-03-16 Impact factor: 15.419

4. The spinosyn family of insecticides: realizing the potential of natural products research.

Authors: Herbert A Kirst
Journal: J Antibiot (Tokyo) Date: 2010-02-12 Impact factor: 2.649

5. Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani.

Authors: Ken Kasahara; Takanori Miyamoto; Takashi Fujimoto; Hiroki Oguri; Tetsuo Tokiwano; Hideaki Oikawa; Yutaka Ebizuka; Isao Fujii
Journal: Chembiochem Date: 2010-06-14 Impact factor: 3.164

6. Mechanistic insights on riboflavin synthase inspired by selective binding of the 6,7-dimethyl-8-ribityllumazine exomethylene anion.

Authors: Ryu-Ryun Kim; Boris Illarionov; Monika Joshi; Mark Cushman; Chan Yong Lee; Wolfgang Eisenreich; Markus Fischer; Adelbert Bacher
Journal: J Am Chem Soc Date: 2010-03-10 Impact factor: 15.419

7. Detailed reaction mechanism of macrophomate synthase. Extraordinary enzyme catalyzing five-step transformation from 2-pyrones to benzoates.

Authors: K Watanabe; T Mie; A Ichihara; H Oikawa; M Honma
Journal: J Biol Chem Date: 2000-12-08 Impact factor: 5.157

Biochemistry: life imitates art.

1. Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.

2. Total synthesis of (-)-spinosyn A.

3. Macrophomate synthase: QM/MM simulations address the Diels-Alder versus Michael-Aldol reaction mechanism.

4. The spinosyn family of insecticides: realizing the potential of natural products research.

5. Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani.

6. Mechanistic insights on riboflavin synthase inspired by selective binding of the 6,7-dimethyl-8-ribityllumazine exomethylene anion.

7. Detailed reaction mechanism of macrophomate synthase. Extraordinary enzyme catalyzing five-step transformation from 2-pyrones to benzoates.

8. Complete reconstitution of a highly reducing iterative polyketide synthase.

9. The putative Diels-Alderase macrophomate synthase is an efficient aldolase.

10. Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A.

Review 1. The Enzymology of Organic Transformations: A Survey of Name Reactions in Biological Systems.

2. An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins.

3. Computational study of a model system of enzyme-mediated [4+2] cycloaddition reaction.