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Literature DB >> 21544073

The tale of TL1A in inflammation.

Abstract

TL1A (also known as TNFSF15) is a tumor necrosis factor (TNF) family member expressed by monocytes, macrophages, dendritic cells (DCs), synovial fibroblasts, and endothelial cells in response to stimulation by cytokines, immune complexes, and microorganisms. Its cell surface receptor, DR3 (also known as TNFSF25, WSL-1, TRAMP, and LARD), is mainly expressed by T cells.

Entities: Disease Gene

Mesh：

Substances：

Year: 2011 PMID： 21544073 DOI： 10.1038/mi.2011.20

Source DB: PubMed Journal: Mucosal Immunol ISSN： 1933-0219 Impact factor: 7.313

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Cited

7 in total

1. TL1A inhibits atherosclerosis in apoE-deficient mice by regulating the phenotype of vascular smooth muscle cells.

Authors: Dan Zhao; Jiaqi Li; Chao Xue; Ke Feng; Lipei Liu; Peng Zeng; Xiaolin Wang; Yuanli Chen; Luyuan Li; Zhisong Zhang; Yajun Duan; Jihong Han; Xiaoxiao Yang
Journal: J Biol Chem Date: 2020-09-22 Impact factor: 5.157

Review 2. New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation.

Authors: Giorgos Bamias; Daniele Corridoni; Theresa T Pizarro; Fabio Cominelli
Journal: Cytokine Date: 2012-07-12 Impact factor: 3.861

3. Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.

Authors: Yonghu Sun; Astrid Irwanto; Licht Toyo-Oka; Myunghee Hong; Hong Liu; Anand Kumar Andiappan; Hyunchul Choi; Yuki Hitomi; Gongqi Yu; Yongxiang Yu; Fangfang Bao; Chuan Wang; Xian Fu; Zhenhua Yue; Honglei Wang; Huimin Zhang; Minae Kawashima; Kaname Kojima; Masao Nagasaki; Minoru Nakamura; Suk-Kyun Yang; Byong Duk Ye; Yosua Denise; Olaf Rotzschke; Kyuyoung Song; Katsushi Tokunaga; Furen Zhang; Jianjun Liu
Journal: Sci Rep Date: 2016-08-10 Impact factor: 4.379

7. Transcriptomic Analysis Suggests the M1 Polarization and Launch of Diverse Programmed Cell Death Pathways in Japanese Encephalitis Virus-Infected Macrophages.

Authors: Zhao-Yang Wang; Zi-Da Zhen; Dong-Ying Fan; Pei-Gang Wang; Jing An
Journal: Viruses Date: 2020-03-24 Impact factor: 5.048

7 in total

The tale of TL1A in inflammation.

1. TL1A inhibits atherosclerosis in apoE-deficient mice by regulating the phenotype of vascular smooth muscle cells.

Review 2. New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation.

3. Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.

4. Changes in TL1A levels and associated cytokines during pathogenesis of diabetic retinopathy.

5. The TL1A-DR3 Axis in Asthma: Membrane-Bound and Secreted TL1A Co-Determined the Development of Airway Remodeling.

6. An Immunity-Related Gene Model Predicts Prognosis in Cholangiocarcinoma.

7. Transcriptomic Analysis Suggests the M1 Polarization and Launch of Diverse Programmed Cell Death Pathways in Japanese Encephalitis Virus-Infected Macrophages.