Literature DB >> 21541000

Drosophila as a model for antiviral immunity.

Jing-Huan Wang1, Susanna Valanne, Mika Rämet.   

Abstract

The fruit fly Drosophila melanogaster has been successfully used to study numerous biological processes including immune response. Flies are naturally infected with more than twenty RNA viruses making it a valid model organism to study host-pathogen interactions during viral infections. The Drosophila antiviral immunity includes RNA interference, activation of the JAK/STAT and other signaling cascades and other mechanisms such as autophagy and interactions with other microorganisms. Here we review Drosophila as an immunological research model as well as recent advances in the field of Drosophila antiviral immunity.

Entities:  

Keywords:  Antiviral; Drosophila; Genetics; Immune signaling; Infection; JAK/STAT; RNA interference; Virus

Year:  2010        PMID： 21541000      PMCID： PMC3083956          DOI： 10.4331/wjbc.v1.i5.151

Source DB:  PubMed          Journal:  World J Biol Chem        ISSN： 1949-8454


  105 in total

1.  Parasite-specific immune response in adult Drosophila melanogaster: a genomic study.

Authors:  Katarina Roxström-Lindquist; Olle Terenius; Ingrid Faye
Journal:  EMBO Rep       Date:  2004-01-23       Impact factor: 8.807

2.  Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila.

Authors:  Delphine Galiana-Arnoux; Catherine Dostert; Anette Schneemann; Jules A Hoffmann; Jean-Luc Imler
Journal:  Nat Immunol       Date:  2006-03-23       Impact factor: 25.606

3.  A Drosophila resource of transgenic RNAi lines for neurogenetics.

Authors:  Jian-Quan Ni; Lu-Ping Liu; Richard Binari; Robert Hardy; Hye-Seok Shim; Amanda Cavallaro; Matthew Booker; Barret D Pfeiffer; Michele Markstein; Hui Wang; Christians Villalta; Todd R Laverty; Lizabeth A Perkins; Norbert Perrimon
Journal:  Genetics       Date:  2009-06-01       Impact factor: 4.562

4.  Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62.

Authors:  P Sanchez; G De Carcer; I V Sandoval; J Moscat; M T Diaz-Meco
Journal:  Mol Cell Biol       Date:  1998-05       Impact factor: 4.272

5.  The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila.

Authors:  Catherine Dostert; Emmanuelle Jouanguy; Phil Irving; Laurent Troxler; Delphine Galiana-Arnoux; Charles Hetru; Jules A Hoffmann; Jean-Luc Imler
Journal:  Nat Immunol       Date:  2005-08-07       Impact factor: 25.606

6.  ATP-sensitive potassium channels mediate survival during infection in mammals and insects.

Authors:  Ben Croker; Karine Crozat; Michael Berger; Yu Xia; Sosathya Sovath; Lana Schaffer; Ioannis Eleftherianos; Jean-Luc Imler; Bruce Beutler
Journal:  Nat Genet       Date:  2007-11-18       Impact factor: 38.330

7.  Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus.

Authors:  Spencer Shelly; Nina Lukinova; Shelly Bambina; Allison Berman; Sara Cherry
Journal:  Immunity       Date:  2009-04-09       Impact factor: 31.745

8.  The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes.

Authors:  A C Spradling; D Stern; A Beaton; E J Rhem; T Laverty; N Mozden; S Misra; G M Rubin
Journal:  Genetics       Date:  1999-09       Impact factor: 4.562

9.  The transcriptional response of Drosophila melanogaster to infection with the sigma virus (Rhabdoviridae).

Authors:  Jennifer Carpenter; Stephan Hutter; John F Baines; Julia Roller; Sarah S Saminadin-Peter; John Parsch; Francis M Jiggins
Journal:  PLoS One       Date:  2009-08-31       Impact factor: 3.240

10.  Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.

Authors:  A H Brand; N Perrimon
Journal:  Development       Date:  1993-06       Impact factor: 6.868
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  8 in total

1.  piRNA pathway is not required for antiviral defense in Drosophila melanogaster.

Authors:  Marine Petit; Vanesa Mongelli; Lionel Frangeul; Hervé Blanc; Francis Jiggins; Maria-Carla Saleh
Journal:  Proc Natl Acad Sci U S A       Date:  2016-06-29       Impact factor: 11.205

Review 2.  Human pathogenic bacteria, fungi, and viruses in Drosophila: disease modeling, lessons, and shortcomings.

Authors:  Stavria Panayidou; Eleni Ioannidou; Yiorgos Apidianakis
Journal:  Virulence       Date:  2014-01-07       Impact factor: 5.882

Review 3.  Conventional and non-conventional Drosophila Toll signaling.

Authors:  Scott A Lindsay; Steven A Wasserman
Journal:  Dev Comp Immunol       Date:  2013-04-28       Impact factor: 3.636

4.  Viral infection: an evolving insight into the signal transduction pathways responsible for the innate immune response.

Authors:  Girish J Kotwal; Steven Hatch; William L Marshall
Journal:  Adv Virol       Date:  2012-09-11

5.  Evolution of JAK-STAT pathway components: mechanisms and role in immune system development.

Authors:  Clifford Liongue; Lynda A O'Sullivan; Monique C Trengove; Alister C Ward
Journal:  PLoS One       Date:  2012-03-07       Impact factor: 3.240

Review 6.  Baculovirus induced transcripts in hemocytes from the larvae of Heliothis virescens.

Authors:  Jonathan E Breitenbach; Kent S Shelby; Holly J R Popham
Journal:  Viruses       Date:  2011-10-28       Impact factor: 5.048

7.  Peptidoglycan recognition protein S2 from silkworm integument: characterization, microbe-induced expression, and involvement in the immune-deficiency pathway.

Authors:  Jie Yang; Xiaonan Wang; Shunming Tang; Zhongyuan Shen; Jinmei Wu
Journal:  J Insect Sci       Date:  2015-03-22       Impact factor: 1.857

Review 8.  The Drosophila JAK-STAT pathway in blood cell formation and immunity.

Authors:  Ismaël Morin-Poulard; Alain Vincent; Michèle Crozatier
Journal:  JAKSTAT       Date:  2013-07-15
  8 in total

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