Literature DB >> 21538763

Feglymycin is an inhibitor of the enzymes MurA and MurC of the peptidoglycan biosynthesis pathway.

Saskia Rausch1, Anne Hänchen, Alexander Denisiuk, Marius Löhken, Tanja Schneider, Roderich D Süssmuth.   

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Year:  2011        PMID: 21538763     DOI: 10.1002/cbic.201100120

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


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  7 in total

1.  UDP-N-acetylmuramic acid l-alanine ligase (MurC) inhibition in a tolC mutant Escherichia coli strain leads to cell death.

Authors:  Vaishali Humnabadkar; K R Prabhakar; Ashwini Narayan; Sreevalli Sharma; Supreeth Guptha; Praveena Manjrekar; Murugan Chinnapattu; Vasanthi Ramachandran; Shahul P Hameed; Sudha Ravishankar; Monalisa Chatterji
Journal:  Antimicrob Agents Chemother       Date:  2014-08-11       Impact factor: 5.191

2.  Lipid Requirements for the Enzymatic Activity of MraY Translocases and in Vitro Reconstitution of the Lipid II Synthesis Pathway.

Authors:  Erik Henrich; Yi Ma; Ina Engels; Daniela Münch; Christian Otten; Tanja Schneider; Beate Henrichfreise; Hans-Georg Sahl; Volker Dötsch; Frank Bernhard
Journal:  J Biol Chem       Date:  2015-11-30       Impact factor: 5.157

Review 3.  Advances in MRSA drug discovery: where are we and where do we need to be?

Authors:  Michio Kurosu; Shajila Siricilla; Katsuhiko Mitachi
Journal:  Expert Opin Drug Discov       Date:  2013-07-06       Impact factor: 6.098

4.  Development of a one-pot assay for screening and identification of Mur pathway inhibitors in Mycobacterium tuberculosis.

Authors:  Kandasamy Eniyan; Anuradha Kumar; Geetha Vani Rayasam; Andrej Perdih; Urmi Bajpai
Journal:  Sci Rep       Date:  2016-10-13       Impact factor: 4.379

5.  Total synthesis of feglymycin based on a linear/convergent hybrid approach using micro-flow amide bond formation.

Authors:  Shinichiro Fuse; Yuto Mifune; Hiroyuki Nakamura; Hiroshi Tanaka
Journal:  Nat Commun       Date:  2016-11-28       Impact factor: 14.919

6.  A New Micromonospora Strain with Antibiotic Activity Isolated from the Microbiome of a Mid-Atlantic Deep-Sea Sponge.

Authors:  Catherine R Back; Henry L Stennett; Sam E Williams; Luoyi Wang; Jorge Ojeda Gomez; Omar M Abdulle; Thomas Duffy; Christopher Neal; Judith Mantell; Mark A Jepson; Katharine R Hendry; David Powell; James E M Stach; Angela E Essex-Lopresti; Christine L Willis; Paul Curnow; Paul R Race
Journal:  Mar Drugs       Date:  2021-02-11       Impact factor: 6.085

7.  A Machine Learning Bioinformatics Method to Predict Biological Activity from Biosynthetic Gene Clusters.

Authors:  Allison S Walker; Jon Clardy
Journal:  J Chem Inf Model       Date:  2021-05-27       Impact factor: 4.956

  7 in total

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