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Literature DB >> 21537464

Regulation of cancer cell migration and invasion by sphingosine-1-phosphate.

Abstract

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that has been implicated in regulation of a number of cancer cell malignant behaviors, including cell proliferation, survival, chemotherapeutic resistance and angiogenesis. However, the effects of S1P on cancer cell migration, invasion and metastasis, are perhaps its most complex, due to the fact that, depending upon the S1P receptors that mediate its responses and the crosstalk with other signaling pathways, S1P can either positively or negatively regulate invasion. This review summarizes the effects of S1P on cancer cell invasion and the mechanisms by which it affects this important aspect of cancer cell behavior.

Entities: Chemical Disease

Keywords: Cancer; Invasion; Metastasis; Sphingolipids

Year: 2010 PMID： 21537464 PMCID： PMC3083934 DOI： 10.4331/wjbc.v1.i10.307

Source DB: PubMed Journal: World J Biol Chem ISSN： 1949-8454

67 in total

1. Sphingosine-1-phosphate inhibits motility of human breast cancer cells independently of cell surface receptors.

Authors: F Wang; J R Van Brocklyn; L Edsall; V E Nava; S Spiegel
Journal: Cancer Res Date: 1999-12-15 Impact factor: 12.701

2. Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells.

Authors: Enkhzol Malchinkhuu; Koichi Sato; Yuta Horiuchi; Chihiro Mogi; Susumu Ohwada; Shogo Ishiuchi; Nobuhito Saito; Hitoshi Kurose; Hideaki Tomura; Fumikazu Okajima
Journal: Oncogene Date: 2005-10-06 Impact factor: 9.867

3. S1P regulation of ovarian carcinoma invasiveness.

Authors: Yoel Smicun; Scott Reierstad; Feng-Qiang Wang; Cathy Lee; David A Fishman
Journal: Gynecol Oncol Date: 2006-09-07 Impact factor: 5.482

4. Sphingosine-1-phosphate stimulates motility and invasiveness of human glioblastoma multiforme cells.

Authors: James R Van Brocklyn; Nicholas Young; Rosemary Roof
Journal: Cancer Lett Date: 2003-09-10 Impact factor: 8.679

5. Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity.

Authors: Kayo Arikawa; Noriko Takuwa; Hironori Yamaguchi; Naotoshi Sugimoto; Joji Kitayama; Hirokazu Nagawa; Kazuhiko Takehara; Yoh Takuwa
Journal: J Biol Chem Date: 2003-06-16 Impact factor: 5.157

6. S1P induced changes in epithelial ovarian cancer proteolysis, invasion, and attachment are mediated by Gi and Rac.

Authors: Kathleen M Devine; Yoel Smicun; Joanie Mayer Hope; David A Fishman
Journal: Gynecol Oncol Date: 2008-05-29 Impact factor: 5.482

7. Inhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinase.

Authors: Mika Suzuki; Hiroshi Kobayashi; Naohiro Kanayama; Yasushi Saga; Mitsuaki Suzuki; Chen-Yong Lin; Robert B Dickson; Toshihiko Terao
Journal: J Biol Chem Date: 2004-01-27 Impact factor: 5.157

8. Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells.

Authors: Steffen E Schnitzer; Andreas Weigert; Jie Zhou; Bernhard Brüne
Journal: Mol Cancer Res Date: 2009-02-24 Impact factor: 5.852

9. Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors.

Authors: Dagmar Meyer zu Heringdorf; Karoly Liliom; Michael Schaefer; Kerstin Danneberg; Jonathan H Jaggar; Gabor Tigyi; Karl H Jakobs
Journal: FEBS Lett Date: 2003-11-20 Impact factor: 4.124

10. Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells.

Authors: Hironori Yamaguchi; Joji Kitayama; Noriko Takuwa; Kayo Arikawa; Isao Inoki; Kazuhiko Takehara; Hirokazu Nagawa; Yoh Takuwa
Journal: Biochem J Date: 2003-09-15 Impact factor: 3.857

13 in total

1. Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways.

Authors: Patrick Quint; Ming Ruan; Larry Pederson; Moustapha Kassem; Jennifer J Westendorf; Sundeep Khosla; Merry Jo Oursler
Journal: J Biol Chem Date: 2013-01-07 Impact factor: 5.157

Review 2. S1PR1 as a Novel Promising Therapeutic Target in Cancer Therapy.

Authors: Narges Rostami; Afshin Nikkhoo; Amir Ajjoolabady; Gholamreza Azizi; Mohammad Hojjat-Farsangi; Ghasem Ghalamfarsa; Bahman Yousefi; Mehdi Yousefi; Farhad Jadidi-Niaragh
Journal: Mol Diagn Ther Date: 2019-08 Impact factor: 4.074

3. Stat3 promotes invasion of esophageal squamous cell carcinoma through up-regulation of MMP2.

Authors: Xaioyan Xuan; Shanshan Li; Xi Lou; Xianzhao Zheng; Yunyun Li; Feng Wang; Yuan Gao; Hongyan Zhang; Hongliu He; Qingru Zeng
Journal: Mol Biol Rep Date: 2014-11-19 Impact factor: 2.316

4. To stay or to leave: Stem cells and progenitor cells navigating the S1P gradient.

Authors: Jingjing Liu; Andrew Hsu; Jen-Fu Lee; Daniel E Cramer; Menq-Jer Lee
Journal: World J Biol Chem Date: 2011-01-26

5. Ginsenoside Rb1 Enhances Keratinocyte Migration by a Sphingosine-1-Phosphate-Dependent Mechanism.

Authors: Kyong-Oh Shin; Sung Jay Choe; Yoshikazu Uchida; Inyong Kim; Yoonhwa Jeong; Kyungho Park
Journal: J Med Food Date: 2018-08-27 Impact factor: 2.786

6. Sphingosine-1-phosphate promotes extravillous trophoblast cell invasion by activating MEK/ERK/MMP-2 signaling pathways via S1P/S1PR1 axis activation.

Authors: Weiwei Yang; Qinghua Li; Zhifang Pan
Journal: PLoS One Date: 2014-09-04 Impact factor: 3.240